Domain arrangement Fusions Fissions Terminal losses Terminal emergences Single domain losses Single domain emergences PF00002 0 1 0 0 0 0 PF00004 PF07724 PF10431 1 0 0 0 0 0 PF00005 0 2 0 0 0 0 PF00006 0 0 3 0 0 0 PF00008 PF02210 1 0 2 0 0 0 PF00009 PF03144 PF00679 0 0 1 0 0 0 PF00010 0 1 0 0 0 0 PF00017 0 2 0 0 0 0 PF00053 PF00052 PF00053 0 1 0 0 0 0 PF00055 0 1 0 0 0 0 PF00056 0 1 0 0 0 0 PF00069 0 1 0 0 0 0 PF00069 PF00415 1 0 0 0 0 0 PF00069 PF00566 PF00581 1 0 0 0 0 0 PF00078 PF00075 1 0 0 0 0 0 PF00091 0 1 0 0 0 0 PF00094 0 0 2 0 0 0 PF00096 PF13894 PF00096 1 0 0 0 0 0 PF00107 0 1 1 0 0 0 PF00109 0 0 12 0 0 0 PF00111 PF01799 PF00941 0 0 3 0 0 0 PF00112 0 1 0 0 0 0 PF00120 0 0 1 0 0 0 PF00130 0 1 0 0 0 0 PF00156 0 1 0 0 0 0 PF00168 PF00616 0 0 7 0 0 0 PF00175 0 0 11 0 0 0 PF00199 0 0 1 0 0 0 PF00215 0 1 0 0 0 0 PF00224 0 0 1 0 0 0 PF00226 0 1 0 0 0 0 PF00240 PF04758 1 0 0 0 0 0 PF00270 PF00271 PF02889 0 2 0 0 0 0 PF00330 0 1 0 0 0 0 PF00350 PF01031 0 0 3 0 0 0 PF00368 0 1 0 0 0 0 PF00385 0 1 0 0 0 0 PF00400 0 2 0 0 0 0 PF00415 PF00651 1 0 0 0 0 0 PF00431 PF00057 1 0 0 0 0 0 PF00498 PF13086 PF13087 1 0 0 0 0 0 PF00501 0 1 0 0 0 0 PF00501 PF00550 1 0 1 0 0 0 PF00557 0 1 0 0 0 0 PF00595 0 1 0 0 0 0 PF00610 0 0 4 0 0 0 PF00615 0 1 0 0 0 0 PF00626 0 1 0 0 0 0 PF00640 0 1 0 0 0 0 PF00664 PF00005 PF00664 1 0 0 0 0 0 PF00679 PF06421 0 0 2 0 0 0 PF00694 0 1 0 0 0 0 PF00750 0 1 0 0 0 0 PF00781 PF00609 0 1 2 0 0 0 PF00788 PF00620 1 0 0 0 0 0 PF00805 0 0 2 0 0 0 PF00955 0 1 0 0 0 0 PF00957 0 1 0 0 0 0 PF00975 0 0 8 0 0 0 PF00989 PF14598 0 1 0 0 0 0 PF01074 0 0 2 0 0 0 PF01085 0 0 1 0 0 0 PF01243 0 0 1 0 0 0 PF01266 PF16901 0 1 0 0 0 0 PF01347 0 1 0 0 0 0 PF01379 0 0 1 0 0 0 PF01380 0 1 0 0 0 0 PF01391 0 1 0 0 0 0 PF01392 PF00057 PF00089 1 0 0 0 0 0 PF01393 0 1 0 0 0 0 PF01400 PF00629 1 0 0 0 0 0 PF01410 0 1 0 0 0 0 PF01565 0 1 0 0 0 0 PF01576 0 1 0 0 0 0 PF01583 0 0 2 0 0 0 PF01835 0 0 9 0 0 0 PF02014 PF06468 1 0 3 0 0 0 PF02014 PF06468 PF00090 1 0 2 0 0 0 PF02138 0 1 1 0 0 0 PF02141 0 0 1 0 0 0 PF02196 0 1 2 0 0 0 PF02197 PF00027 1 0 0 0 0 0 PF02204 0 1 2 0 0 0 PF02204 PF00788 0 1 0 0 0 0 PF02209 0 1 0 0 0 0 PF02318 PF00168 1 0 0 0 0 0 PF02736 PF00063 0 1 3 0 0 0 PF02793 0 1 0 0 0 0 PF02820 PF12140 PF00536 1 0 0 0 0 0 PF02833 0 0 1 0 0 0 PF02836 0 0 2 0 0 0 PF02866 0 1 0 0 0 0 PF02881 PF00448 0 0 2 0 0 0 PF02889 0 1 5 0 0 0 PF02892 PF05699 1 0 0 0 0 0 PF02913 0 1 0 0 0 0 PF02926 PF01170 1 0 0 0 0 0 PF03028 0 1 0 0 0 0 PF03124 0 0 1 0 0 0 PF03253 0 0 0 0 1 0 PF03722 PF00372 0 1 0 0 0 0 PF03723 0 1 0 0 0 0 PF03953 0 1 0 0 0 0 PF04083 PF12146 1 0 0 0 0 0 PF04377 0 0 1 0 0 0 PF04488 0 0 1 0 0 0 PF04724 0 0 0 0 1 0 PF04937 PF05699 1 0 0 0 0 0 PF04960 0 1 0 0 0 0 PF05033 PF00856 0 1 0 0 0 0 PF05057 0 0 1 0 0 0 PF05195 0 1 0 0 0 0 PF05222 0 0 5 0 0 0 PF05225 PF03184 1 0 0 0 0 0 PF05225 PF03221 PF03184 1 0 0 0 0 0 PF05362 0 0 2 0 0 0 PF05746 0 1 0 0 0 0 PF06333 0 1 0 0 0 0 PF06472 0 1 0 0 0 0 PF07529 PF07533 PF00176 PF00271 PF14619 PF00439 0 0 1 0 0 0 PF07565 0 1 0 0 0 0 PF07653 PF00625 1 0 0 0 0 0 PF07700 0 1 0 0 0 0 PF07701 PF00211 0 1 0 0 0 0 PF07724 0 0 1 0 0 0 PF07731 0 1 0 0 0 0 PF07732 PF00394 0 1 0 0 0 0 PF07748 0 0 2 0 0 0 PF07776 PF13912 PF13894 PF13912 1 0 0 0 0 0 PF07970 0 0 1 0 0 0 PF08240 0 1 0 0 0 0 PF08246 0 1 0 0 0 0 PF08337 0 0 3 0 0 0 PF08393 PF12774 PF07728 PF12775 PF12780 PF12777 PF12781 0 1 0 0 0 0 PF08416 0 1 0 0 0 0 PF08645 0 1 0 0 0 0 PF08755 0 0 1 0 0 0 PF09172 PF00094 0 1 0 0 0 0 PF10607 0 1 0 0 0 0 PF11597 0 1 0 0 0 0 PF12053 0 1 0 0 0 0 PF12349 0 1 0 0 0 0 PF12473 PF00566 0 1 0 0 0 0 PF12474 0 1 0 0 0 0 PF12698 0 1 3 0 0 0 PF12774 PF12775 PF12780 PF12777 PF12781 PF03028 0 0 1 0 0 0 PF12775 PF12780 PF12777 PF12781 PF03028 0 0 9 0 0 0 PF12781 PF03028 0 0 18 0 0 0 PF12796 0 2 0 0 0 0 PF12796 PF00023 0 1 0 0 0 0 PF12796 PF03020 1 0 0 0 0 0 PF12796 PF13606 PF12796 1 0 0 0 0 0 PF13086 0 1 0 0 0 0 PF13087 0 1 0 0 0 0 PF13193 0 1 2 0 0 0 PF13242 0 0 1 0 0 0 PF13246 PF16212 0 1 0 0 0 0 PF13307 0 0 3 0 0 0 PF13359 0 1 0 0 0 0 PF13445 0 1 2 0 0 0 PF13450 0 0 2 0 0 0 PF13499 0 1 0 0 0 0 PF13520 0 1 0 0 0 0 PF13522 0 1 0 0 0 0 PF13613 0 1 0 0 0 0 PF13637 PF00023 PF12796 1 0 0 0 0 0 PF13671 0 1 0 0 0 0 PF13774 0 1 0 0 0 0 PF13906 0 1 0 0 0 0 PF13912 PF12874 PF13912 1 0 0 0 0 0 PF13912 PF13894 PF13912 PF12874 1 0 0 0 0 0 PF13921 0 0 1 0 0 0 PF14214 PF05970 1 0 0 0 0 0 PF14223 PF00098 1 0 0 0 0 0 PF14604 PF00018 1 0 0 0 0 0 PF14670 0 0 4 0 0 0 PF14748 0 0 1 0 0 0 PF15043 0 0 0 0 1 0 PF15684 0 0 0 0 1 0 PF16050 0 0 1 0 0 0 PF16209 PF00122 0 1 0 0 0 0 PF16589 0 0 1 0 0 0 PF17120 0 1 0 0 0 0