Domain arrangement Fusions Fissions Terminal losses Terminal emergences Single domain losses Single domain emergences PF00009 PF03144 PF14492 0 0 2 0 0 0 PF00018 PF00017 1 0 0 0 0 0 PF00018 PF00017 PF07714 1 0 0 0 0 0 PF00031 PF08246 PF00112 1 0 0 0 0 0 PF00041 PF16066 1 0 0 0 0 0 PF00056 0 0 1 0 0 0 PF00057 0 1 0 0 0 0 PF00063 PF00612 PF01576 1 0 1 0 0 0 PF00130 PF00780 1 0 0 0 0 0 PF00400 PF08662 1 0 0 0 0 0 PF00575 PF00271 PF04408 PF07717 1 0 0 0 0 0 PF00578 0 0 1 0 0 0 PF00612 PF00004 1 0 0 0 0 0 PF00638 PF00641 PF00638 0 0 2 0 0 0 PF00642 PF00097 1 0 0 0 0 0 PF00651 PF00505 1 0 0 0 0 0 PF00667 PF00175 0 0 3 0 0 0 PF00704 PF01607 PF00704 1 0 0 0 0 0 PF00787 PF00433 1 0 0 0 0 0 PF00787 PF00788 1 0 0 0 0 0 PF00856 PF13912 1 0 0 0 0 0 PF01094 0 1 0 0 0 0 PF01094 PF10613 1 0 2 0 0 0 PF01207 PF00035 1 0 0 0 0 0 PF01243 0 0 1 0 0 0 PF01411 0 0 3 0 0 0 PF01426 PF00145 1 0 2 0 0 0 PF01530 PF01853 1 0 0 0 0 0 PF01562 0 1 0 0 0 0 PF02170 0 1 0 0 0 0 PF02171 0 1 0 0 0 0 PF02177 0 0 3 0 0 0 PF02729 PF00185 0 0 7 0 0 0 PF02759 PF13901 1 0 0 0 0 0 PF02798 PF14497 PF02798 PF14497 1 0 0 0 0 0 PF02854 PF09088 0 0 1 0 0 0 PF02893 PF00566 1 0 0 0 0 0 PF03022 0 0 0 0 0 1 PF03114 PF00018 1 0 0 0 0 0 PF03224 0 0 1 0 0 0 PF03485 PF00750 0 1 0 0 0 0 PF03810 PF02985 1 0 0 0 0 0 PF04408 0 1 0 0 0 0 PF04832 0 0 0 0 1 0 PF04849 0 0 1 0 0 0 PF04970 0 0 0 0 1 0 PF05021 0 0 2 0 0 0 PF05225 PF03184 1 0 0 0 0 0 PF05236 0 0 1 0 0 0 PF05485 PF12017 1 0 0 0 0 0 PF05605 0 0 1 0 0 0 PF05712 0 1 0 0 0 0 PF05746 0 1 0 0 0 0 PF07502 0 1 0 0 0 0 PF07562 PF00003 0 1 0 0 0 0 PF07648 PF13927 PF07679 1 0 0 0 0 0 PF07717 0 1 0 0 0 0 PF08172 0 0 0 0 1 0 PF08513 0 1 0 0 0 0 PF09379 PF00373 1 0 7 0 0 0 PF10607 0 1 0 0 0 0 PF11018 0 0 0 0 0 1 PF11717 0 1 2 0 0 0 PF11901 0 1 0 0 0 0 PF12248 0 1 0 0 0 0 PF12569 0 1 0 0 0 0 PF12780 PF12777 PF12781 PF03028 0 0 12 0 0 0 PF12999 0 0 2 0 0 0 PF13015 0 0 2 0 0 0 PF13181 0 1 0 0 0 0 PF13325 PF00498 1 0 0 0 0 0 PF13574 PF00200 0 1 0 0 0 0 PF13637 PF00023 1 0 0 0 0 0 PF13833 PF13202 1 0 0 0 0 0 PF13855 PF12799 1 0 0 0 0 0 PF13855 PF13927 PF07679 1 0 0 0 0 0 PF13912 PF13894 PF13912 1 0 0 0 0 0 PF14572 0 0 1 0 0 0 PF14580 PF00612 1 0 0 0 0 0 PF15802 0 0 0 0 1 0 PF15929 0 0 0 0 0 1 PF16172 0 0 2 0 0 0 PF16746 PF00169 PF01412 PF12796 PF00018 1 0 0 0 0 0 PF16880 0 0 2 0 0 0