GO:0003964	RNA-directed DNA polymerase activity	Gains
GO:0034061	DNA polymerase activity	Gains
GO:0016779	nucleotidyltransferase activity	Gains
GO:0140097	catalytic activity, acting on DNA	Gains
GO:0003676	nucleic acid binding	Gains
GO:0004984	olfactory receptor activity	Gains
GO:0070001	aspartic-type peptidase activity	Gains
GO:0004190	aspartic-type endopeptidase activity	Gains
GO:0005549	odorant binding	Gains
GO:0016772	transferase activity, transferring phosphorus-containing groups	Gains
GO:1901363	heterocyclic compound binding	Gains
GO:0097159	organic cyclic compound binding	Gains
GO:0004518	nuclease activity	Gains
GO:0046914	transition metal ion binding	Gains
GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	Gains
GO:0004523	RNA-DNA hybrid ribonuclease activity	Gains
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	Gains
GO:0008270	zinc ion binding	Gains
GO:0003723	RNA binding	Gains
GO:0004888	transmembrane signaling receptor activity	Gains
GO:0004521	endoribonuclease activity	Gains
GO:0004519	endonuclease activity	Gains
GO:0099600	transmembrane receptor activity	Gains
GO:0004803	transposase activity	Gains
GO:0004497	monooxygenase activity	Gains
GO:0004540	ribonuclease activity	Gains
GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	Gains
GO:0016740	transferase activity	Gains
GO:0038023	signaling receptor activity	Gains
GO:0140098	catalytic activity, acting on RNA	Gains
GO:0004871	signal transducer activity	Gains
GO:0004930	G-protein coupled receptor activity	Gains
GO:0004104	cholinesterase activity	Gains
GO:0004175	endopeptidase activity	Gains
GO:0003677	DNA binding	Gains
GO:0070011	peptidase activity, acting on L-amino acid peptides	Gains
GO:0004312	fatty acid synthase activity	Gains
GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity	Gains
GO:0016296	palmitoyl-[acyl-carrier-protein] hydrolase activity	Gains
GO:0016297	acyl-[acyl-carrier-protein] hydrolase activity	Gains
GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity	Gains
GO:0004313	[acyl-carrier-protein] S-acetyltransferase activity	Gains
GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	Gains
GO:0004317	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity	Gains
GO:0004319	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity	Gains
GO:0019171	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	Gains
GO:0097747	RNA polymerase activity	Gains
GO:0034062	5'-3' RNA polymerase activity	Gains
GO:0016788	hydrolase activity, acting on ester bonds	Gains
GO:0008174	mRNA methyltransferase activity	Gains
GO:0052689	carboxylic ester hydrolase activity	Gains
GO:0004602	glutathione peroxidase activity	Gains
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Gains
GO:0070330	aromatase activity	Gains
GO:0005506	iron ion binding	Gains
GO:0046906	tetrapyrrole binding	Gains
GO:0004872	receptor activity	Gains
GO:0060089	molecular transducer activity	Gains
GO:0004555	alpha,alpha-trehalase activity	Gains
GO:0003963	RNA-3'-phosphate cyclase activity	Gains
GO:0016420	malonyltransferase activity	Gains
GO:0016419	S-malonyltransferase activity	Gains
GO:0015927	trehalase activity	Gains
GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity	Gains
GO:0004482	mRNA (guanine-N7-)-methyltransferase activity	Gains
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Gains
GO:0003990	acetylcholinesterase activity	Gains
GO:0008233	peptidase activity	Gains
GO:0005488	binding	Gains
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Gains
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	Gains
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Gains
GO:0004806	triglyceride lipase activity	Gains
GO:0016418	S-acetyltransferase activity	Gains
GO:0031683	G-protein beta/gamma-subunit complex binding	Gains
GO:0004144	diacylglycerol O-acyltransferase activity	Gains
GO:0016798	hydrolase activity, acting on glycosyl bonds	Gains
GO:0020037	heme binding	Gains
GO:0015926	glucosidase activity	Gains
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Gains
GO:0008010	structural constituent of chitin-based larval cuticle	Gains
GO:0016229	steroid dehydrogenase activity	Gains
GO:0010181	FMN binding	Gains
GO:0003678	DNA helicase activity	Gains
GO:0005527	macrolide binding	Gains
GO:0005528	FK506 binding	Gains
GO:0004869	cysteine-type endopeptidase inhibitor activity	Gains
GO:0005549	odorant binding	Losses
GO:0099600	transmembrane receptor activity	Losses
GO:0004888	transmembrane signaling receptor activity	Losses
GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	Losses
GO:0005216	ion channel activity	Losses
GO:0022838	substrate-specific channel activity	Losses
GO:0004984	olfactory receptor activity	Losses
GO:0015267	channel activity	Losses
GO:0022803	passive transmembrane transporter activity	Losses
GO:0004930	G-protein coupled receptor activity	Losses
GO:0060089	molecular transducer activity	Losses
GO:0038023	signaling receptor activity	Losses
GO:0004872	receptor activity	Losses
GO:0022836	gated channel activity	Losses
GO:0004871	signal transducer activity	Losses
GO:0015075	ion transmembrane transporter activity	Losses
GO:0015276	ligand-gated ion channel activity	Losses
GO:0022834	ligand-gated channel activity	Losses
GO:0030553	cGMP binding	Losses
GO:0005230	extracellular ligand-gated ion channel activity	Losses
GO:0005261	cation channel activity	Losses
GO:0003700	DNA binding transcription factor activity	Losses
GO:0005215	transporter activity	Losses
GO:0005118	sevenless binding	Losses
GO:0005179	hormone activity	Losses
GO:0022857	transmembrane transporter activity	Losses
GO:0022891	substrate-specific transmembrane transporter activity	Losses
GO:0004692	cGMP-dependent protein kinase activity	Losses
GO:0019992	diacylglycerol binding	Losses
GO:0030551	cyclic nucleotide binding	Losses
GO:0030545	receptor regulator activity	Losses
GO:0022892	substrate-specific transporter activity	Losses
GO:0032182	ubiquitin-like protein binding	Losses
GO:0008307	structural constituent of muscle	Losses
GO:0022890	inorganic cation transmembrane transporter activity	Losses
GO:0005102	receptor binding	Losses
GO:0004687	myosin light chain kinase activity	Losses
GO:0016840	carbon-nitrogen lyase activity	Losses
GO:0048018	receptor ligand activity	Losses
GO:0015077	monovalent inorganic cation transmembrane transporter activity	Losses
GO:0140110	transcription regulator activity	Losses
GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	Losses
GO:0005549	odorant binding	Extinctions
GO:0004984	olfactory receptor activity	Extinctions
GO:0004930	G-protein coupled receptor activity	Extinctions
GO:0099600	transmembrane receptor activity	Extinctions
GO:0004888	transmembrane signaling receptor activity	Extinctions
GO:0032182	ubiquitin-like protein binding	Extinctions
GO:0016840	carbon-nitrogen lyase activity	Extinctions
GO:0030545	receptor regulator activity	Extinctions
GO:0005179	hormone activity	Extinctions
GO:0038023	signaling receptor activity	Extinctions
GO:0005509	calcium ion binding	Extinctions
GO:0008121	ubiquinol-cytochrome-c reductase activity	Extinctions
GO:0016597	amino acid binding	Extinctions
GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	Extinctions
GO:0004871	signal transducer activity	Extinctions
GO:0050797	thymidylate synthase (FAD) activity	Extinctions
GO:0004794	L-threonine ammonia-lyase activity	Extinctions
GO:0005550	pheromone binding	Extinctions
GO:0004808	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	Extinctions
GO:0046403	polynucleotide 3'-phosphatase activity	Extinctions
GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	Extinctions
GO:0001888	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	Extinctions
GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity	Extinctions
GO:0004528	phosphodiesterase I activity	Extinctions
GO:0005094	Rho GDP-dissociation inhibitor activity	Extinctions
GO:0035529	NADH pyrophosphatase activity	Extinctions
GO:0004056	argininosuccinate lyase activity	Extinctions
GO:0032183	SUMO binding	Extinctions
GO:0008446	GDP-mannose 4,6-dehydratase activity	Extinctions
GO:0016841	ammonia-lyase activity	Extinctions
GO:0008255	ecdysis-triggering hormone activity	Extinctions
GO:0003726	double-stranded RNA adenosine deaminase activity	Extinctions
GO:0003883	CTP synthase activity	Extinctions
GO:0051733	polydeoxyribonucleotide kinase activity	Extinctions
GO:0051734	ATP-dependent polynucleotide kinase activity	Extinctions