Domain arrangement Fusions Fissions Terminal losses Terminal emergences Single domain losses Single domain emergences PF00009 PF00679 PF06421 1 0 0 0 0 0 PF00014 0 0 5 0 0 0 PF00047 PF00041 1 0 0 0 0 0 PF00069 PF13593 1 0 0 0 0 0 PF00083 PF07690 1 0 0 0 0 0 PF00097 PF02190 0 0 1 0 0 0 PF00149 PF04152 0 1 0 0 0 0 PF00149 PF05011 1 0 0 0 0 0 PF00151 0 2 0 0 0 0 PF00168 PF08151 PF00168 PF08150 PF00168 0 0 1 0 0 0 PF00249 PF04433 0 0 1 0 0 0 PF00326 0 1 0 0 0 0 PF00366 0 0 1 0 0 0 PF00400 0 1 0 0 0 0 PF00411 0 1 0 0 0 0 PF00413 0 0 1 0 0 0 PF00530 0 0 1 0 0 0 PF00533 0 1 5 0 0 0 PF00595 PF00168 1 0 0 0 0 0 PF00643 PF00025 1 0 0 0 0 0 PF00789 0 1 0 0 0 0 PF00804 0 1 0 0 0 0 PF00930 0 1 0 0 0 0 PF01347 PF09172 0 0 3 0 0 0 PF01530 0 1 0 0 0 0 PF01562 PF01421 PF00090 0 0 5 0 0 0 PF01853 0 1 1 0 0 0 PF02460 0 1 0 0 0 0 PF02630 0 1 0 0 0 0 PF02893 PF02138 PF00400 1 0 0 0 0 0 PF03530 0 0 2 0 0 0 PF03920 0 1 0 0 0 0 PF04675 PF01068 PF04679 0 0 5 0 0 0 PF04851 PF00271 PF00079 1 0 0 0 0 0 PF05739 0 2 0 0 0 0 PF07648 PF07679 1 0 0 0 0 0 PF07677 0 0 5 0 0 0 PF07679 PF13927 PF07679 PF00041 1 0 1 0 0 0 PF07686 PF13927 PF07679 PF00041 1 0 0 0 0 0 PF07776 PF13912 PF13894 PF12874 1 0 0 0 0 0 PF07776 PF13912 PF13894 PF13912 1 0 2 0 0 0 PF08729 PF14075 PF16009 1 0 0 0 0 0 PF08824 PF12026 0 1 0 0 0 0 PF11470 0 1 0 0 0 0 PF11620 PF02198 PF00178 0 1 0 0 0 0 PF12108 PF16837 PF13297 PF11931 0 1 0 0 0 0 PF12171 PF12874 1 0 0 0 0 0 PF12349 0 1 1 0 0 0 PF12796 PF01734 1 0 1 0 0 0 PF12796 PF13637 PF01529 1 0 0 0 0 0 PF12796 PF13857 1 0 0 0 0 0 PF12874 PF13894 PF12874 1 0 0 0 0 0 PF12895 PF00515 0 1 0 0 0 0 PF13181 0 1 0 0 0 0 PF13242 0 0 1 0 0 0 PF13302 PF04117 1 0 0 0 0 0 PF13359 0 0 0 0 1 0 PF13426 0 1 0 0 0 0 PF13637 0 1 0 0 0 0 PF13855 PF13927 PF07679 1 0 0 0 0 0 PF13894 PF12874 PF13894 1 0 0 0 0 0 PF13923 0 1 0 0 0 0 PF13927 PF07714 1 0 0 0 0 0 PF14244 0 0 0 0 1 0 PF14523 0 1 0 0 0 0 PF14555 PF13899 PF00789 1 0 0 0 0 0 PF14559 0 1 1 0 0 0 PF14598 0 1 3 0 0 0 PF14604 0 2 0 0 0 0 PF14604 PF07653 0 1 0 0 0 0 PF15280 PF14924 1 0 0 0 0 0 PF16368 PF16367 PF16366 0 1 0 0 0 0