GO:0005201	extracellular matrix structural constituent	Gains
GO:0042302	structural constituent of cuticle	Gains
GO:0030023	extracellular matrix constituent conferring elasticity	Gains
GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity	Gains
GO:0097493	structural molecule activity conferring elasticity	Gains
GO:0070735	protein-glycine ligase activity	Gains
GO:0070736	protein-glycine ligase activity, initiating	Gains
GO:0070737	protein-glycine ligase activity, elongating	Gains
GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	Gains
GO:0052826	inositol hexakisphosphate 2-phosphatase activity	Gains
GO:0008106	alcohol dehydrogenase (NADP+) activity	Gains
GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	Gains
GO:0005212	structural constituent of eye lens	Gains
GO:0004446	inositol-hexakisphosphate phosphatase activity	Gains
GO:0043539	protein serine/threonine kinase activator activity	Gains
GO:0004032	alditol:NADP+ 1-oxidoreductase activity	Gains
GO:0004033	aldo-keto reductase (NADP) activity	Gains
GO:0003964	RNA-directed DNA polymerase activity	Gains
GO:0003944	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity	Gains
GO:0004035	alkaline phosphatase activity	Gains
GO:0004190	aspartic-type endopeptidase activity	Gains
GO:0070001	aspartic-type peptidase activity	Gains
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Gains
GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity	Gains
GO:0052591	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity	Gains
GO:0004368	glycerol-3-phosphate dehydrogenase activity	Gains
GO:0001786	phosphatidylserine binding	Gains
GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	Gains
GO:0004619	phosphoglycerate mutase activity	Gains
GO:0034061	DNA polymerase activity	Gains
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	Gains
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	Gains
GO:0030295	protein kinase activator activity	Gains
GO:0072341	modified amino acid binding	Gains
GO:0019209	kinase activator activity	Gains
GO:0008061	chitin binding	Gains
GO:0042578	phosphoric ester hydrolase activity	Gains
GO:0016791	phosphatase activity	Gains
GO:0015299	solute:proton antiporter activity	Gains
GO:0004835	tubulin-tyrosine ligase activity	Gains
GO:0001047	core promoter binding	Gains
GO:0003964	RNA-directed DNA polymerase activity	Losses
GO:0034061	DNA polymerase activity	Losses
GO:0140097	catalytic activity, acting on DNA	Losses
GO:0016779	nucleotidyltransferase activity	Losses
GO:0005549	odorant binding	Losses
GO:0004803	transposase activity	Losses
GO:0004518	nuclease activity	Losses
GO:0004519	endonuclease activity	Losses
GO:0004190	aspartic-type endopeptidase activity	Losses
GO:0070001	aspartic-type peptidase activity	Losses
GO:0004984	olfactory receptor activity	Losses
GO:0003723	RNA binding	Losses
GO:0003676	nucleic acid binding	Losses
GO:0046872	metal ion binding	Losses
GO:0043169	cation binding	Losses
GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	Losses
GO:0004523	RNA-DNA hybrid ribonuclease activity	Losses
GO:0016772	transferase activity, transferring phosphorus-containing groups	Losses
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	Losses
GO:0004521	endoribonuclease activity	Losses
GO:0045174	glutathione dehydrogenase (ascorbate) activity	Losses
GO:0034185	apolipoprotein binding	Losses
GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity	Losses
GO:0005550	pheromone binding	Losses
GO:0050353	trimethyllysine dioxygenase activity	Losses
GO:0004734	pyrimidodiazepine synthase activity	Losses
GO:0016502	nucleotide receptor activity	Losses
GO:0016672	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor	Losses
GO:0016648	oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor	Losses
GO:0001614	purinergic nucleotide receptor activity	Losses
GO:0097109	neuroligin family protein binding	Losses
GO:0008336	gamma-butyrobetaine dioxygenase activity	Losses
GO:0008422	beta-glucosidase activity	Losses
GO:0008270	zinc ion binding	Losses
GO:0005488	binding	Losses
GO:0008233	peptidase activity	Losses
GO:0003677	DNA binding	Losses
GO:0046914	transition metal ion binding	Losses
GO:0070628	proteasome binding	Losses
GO:0017018	myosin phosphatase activity	Losses
GO:0035586	purinergic receptor activity	Losses
GO:0015037	peptide disulfide oxidoreductase activity	Losses
GO:0015038	glutathione disulfide oxidoreductase activity	Losses
GO:0004594	pantothenate kinase activity	Losses
GO:0004555	alpha,alpha-trehalase activity	Losses
GO:0015927	trehalase activity	Losses
GO:0003939	L-iditol 2-dehydrogenase activity	Losses
GO:0070011	peptidase activity, acting on L-amino acid peptides	Losses
GO:0004175	endopeptidase activity	Losses
GO:0016788	hydrolase activity, acting on ester bonds	Losses
GO:0004540	ribonuclease activity	Losses
GO:0016454	C-palmitoyltransferase activity	Losses
GO:0004758	serine C-palmitoyltransferase activity	Losses
GO:0008970	phosphatidylcholine 1-acylhydrolase activity	Losses
GO:0015439	heme-transporting ATPase activity	Losses
GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity	Losses
GO:0052739	phosphatidylserine 1-acylhydrolase activity	Losses
GO:0016209	antioxidant activity	Losses
GO:0015232	heme transporter activity	Losses
GO:0030955	potassium ion binding	Losses
GO:0031420	alkali metal ion binding	Losses
GO:0070006	metalloaminopeptidase activity	Losses
GO:0019992	diacylglycerol binding	Losses
GO:0008527	taste receptor activity	Losses
GO:0004774	succinate-CoA ligase activity	Losses
GO:0004775	succinate-CoA ligase (ADP-forming) activity	Losses
GO:0004743	pyruvate kinase activity	Losses
GO:0032182	ubiquitin-like protein binding	Losses
GO:0043130	ubiquitin binding	Losses
GO:0003964	RNA-directed DNA polymerase activity	Extinctions
GO:0034061	DNA polymerase activity	Extinctions
GO:0140097	catalytic activity, acting on DNA	Extinctions
GO:0016779	nucleotidyltransferase activity	Extinctions
GO:0004518	nuclease activity	Extinctions
GO:0005549	odorant binding	Extinctions
GO:0004519	endonuclease activity	Extinctions
GO:0003676	nucleic acid binding	Extinctions
GO:0004190	aspartic-type endopeptidase activity	Extinctions
GO:0070001	aspartic-type peptidase activity	Extinctions
GO:0046872	metal ion binding	Extinctions
GO:0043169	cation binding	Extinctions
GO:0003723	RNA binding	Extinctions
GO:0005550	pheromone binding	Extinctions
GO:0050353	trimethyllysine dioxygenase activity	Extinctions
GO:0016502	nucleotide receptor activity	Extinctions
GO:0001614	purinergic nucleotide receptor activity	Extinctions
GO:0008336	gamma-butyrobetaine dioxygenase activity	Extinctions
GO:0070628	proteasome binding	Extinctions
GO:0035586	purinergic receptor activity	Extinctions
GO:0008233	peptidase activity	Extinctions
GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	Extinctions
GO:0016772	transferase activity, transferring phosphorus-containing groups	Extinctions
GO:0016454	C-palmitoyltransferase activity	Extinctions
GO:0004758	serine C-palmitoyltransferase activity	Extinctions
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	Extinctions
GO:0030955	potassium ion binding	Extinctions
GO:0031420	alkali metal ion binding	Extinctions
GO:0070006	metalloaminopeptidase activity	Extinctions
GO:0019992	diacylglycerol binding	Extinctions
GO:0004743	pyruvate kinase activity	Extinctions
GO:0032182	ubiquitin-like protein binding	Extinctions
GO:0043130	ubiquitin binding	Extinctions
GO:0070011	peptidase activity, acting on L-amino acid peptides	Extinctions
GO:0016788	hydrolase activity, acting on ester bonds	Extinctions
GO:0004521	endoribonuclease activity	Extinctions