Domain arrangement Fusions Fissions Terminal losses Terminal emergences Single domain losses Single domain emergences PF00002 0 1 0 0 0 0 PF00008 PF02210 1 0 4 0 0 0 PF00009 PF03144 PF11987 1 0 0 0 0 0 PF00010 0 1 0 0 0 0 PF00041 PF07679 PF00041 1 0 9 0 0 0 PF00047 PF08205 1 0 0 0 0 0 PF00057 PF15494 PF00089 0 0 1 0 0 0 PF00076 0 1 0 0 0 0 PF00130 PF00781 PF00609 PF07647 1 0 0 0 0 0 PF00168 0 1 0 0 0 0 PF00168 PF00130 PF00069 PF00433 1 0 0 0 0 0 PF00224 PF02887 0 2 0 0 0 0 PF00225 PF00400 1 0 0 0 0 0 PF00226 0 1 0 0 0 0 PF00288 PF08544 0 0 1 0 0 0 PF00412 0 1 0 0 0 0 PF00447 0 0 1 0 0 0 PF00472 0 0 1 0 0 0 PF00531 PF00069 1 0 0 0 0 0 PF00575 PF05843 1 0 0 0 0 0 PF00611 0 1 3 0 0 0 PF00627 0 1 8 0 0 0 PF00628 PF16737 PF00628 PF00498 1 0 0 0 0 0 PF00642 PF00076 1 0 0 0 0 0 PF00651 PF07707 PF07534 1 0 0 0 0 0 PF00722 0 0 1 0 0 0 PF00789 0 1 0 0 0 0 PF00989 PF14598 0 1 0 0 0 0 PF01189 0 1 0 0 0 0 PF01369 0 1 2 0 0 0 PF01433 0 1 0 0 0 0 PF01436 0 1 0 0 0 0 PF01562 PF01421 PF00090 PF05986 PF00090 PF08685 1 0 0 0 0 0 PF02014 PF03351 1 0 0 0 0 0 PF02136 PF03943 0 1 1 0 0 0 PF02318 0 1 0 0 0 0 PF02828 PF00595 0 1 0 0 0 0 PF02866 0 0 1 0 0 0 PF03098 0 1 0 0 0 0 PF04083 PF12146 1 0 0 0 0 0 PF04641 PF00160 1 0 0 0 0 0 PF04818 0 1 2 0 0 0 PF05193 0 0 4 0 0 0 PF05207 0 1 0 0 0 0 PF05277 0 0 0 0 1 0 PF05347 0 1 0 0 0 0 PF05972 PF05923 0 0 1 0 0 0 PF06652 0 1 0 0 0 0 PF07648 PF13927 PF07679 1 0 0 0 0 0 PF07653 PF00625 0 1 0 0 0 0 PF07686 PF13927 PF07679 1 0 0 0 0 0 PF07757 0 1 0 0 0 0 PF08205 PF13927 PF00041 1 0 0 0 0 0 PF08368 0 0 2 0 0 0 PF08572 PF06544 0 1 0 0 0 0 PF08614 PF00400 1 0 0 0 0 0 PF09324 0 0 3 0 0 0 PF09446 0 1 0 0 0 0 PF11838 0 1 0 0 0 0 PF12796 PF01734 1 0 0 0 0 0 PF12799 PF13855 1 0 0 0 0 0 PF13445 0 1 2 0 0 0 PF13516 0 1 0 0 0 0 PF13855 PF00560 PF13855 1 0 4 0 0 0 PF13912 PF13894 1 0 0 0 0 0 PF14051 PF00628 1 0 0 0 0 0 PF14604 0 1 0 0 0 0 PF15410 0 1 0 0 0 0 PF15949 0 1 0 0 0 0 PF16172 0 0 2 0 0 0