EOG815JW5 GO:0007165 23/94 signal transduction biological_process "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] EOG815JW5 GO:0005622 23/94 intracellular cellular_component "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] EOG815JW5 GO:0046961 1/94 proton-transporting ATPase activity, rotational mechanism molecular_function "Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism." [EC:3.6.3.14] EOG815JW5 GO:0033178 1/94 proton-transporting two-sector ATPase complex, catalytic domain cellular_component "A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled." [GOC:mah, PMID:10838056] EOG815JW5 GO:0007480 1/94 imaginal disc-derived leg morphogenesis biological_process "The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] EOG815JW5 GO:0015991 1/94 ATP hydrolysis coupled proton transport biological_process "The transport of protons against an electrochemical gradient, using energy from ATP hydrolysis." [GOC:mah, GOC:vw]