EOG82VBW4 GO:0051536 28/106 iron-sulfur cluster binding molecular_function "Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms." [GOC:ai] EOG82VBW4 GO:0006222 26/106 UMP biosynthetic process biological_process "The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate." [ISBN:0198506732] EOG82VBW4 GO:0004158 22/106 dihydroorotate oxidase activity molecular_function "Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) + orotate." [EC:1.3.3.1, RHEA:15444] EOG82VBW4 GO:0005737 22/106 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG82VBW4 GO:0006207 16/106 'de novo' pyrimidine nucleobase biosynthetic process biological_process "The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors." [GOC:mah, ISBN:0716720094] EOG82VBW4 GO:0004152 4/106 dihydroorotate dehydrogenase activity molecular_function "Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate." [EC:1.3.5.2, RHEA:18076] EOG82VBW4 GO:0017113 2/106 dihydropyrimidine dehydrogenase (NADP+) activity molecular_function "Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+." [EC:1.3.1.2] EOG82VBW4 GO:0052888 1/106 obsolete OBSOLETE:dihydroorotate oxidase (fumarate) activity molecular_function "Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate." [EC:1.3.98.1, RHEA:30062] EOG82VBW4 GO:0003824 1/106 catalytic activity molecular_function "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732]