EOG83FKBQ GO:0051001 1/88 negative regulation of nitric-oxide synthase activity biological_process "Any process that stops or reduces the activity of the enzyme nitric-oxide synthase." [GOC:ai] EOG83FKBQ GO:0071013 1/88 catalytic step 2 spliceosome cellular_component "A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs." [GOC:ab, GOC:krc, GOC:mah, ISBN:0879695897, ISBN:0879697393, PMID:18322460, PMID:19239890] EOG83FKBQ GO:0005634 1/88 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG83FKBQ GO:0000398 1/88 mRNA splicing, via spliceosome biological_process "The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." [GOC:krc, ISBN:0198506732, ISBN:0879695897] EOG83FKBQ GO:0043086 1/88 negative regulation of catalytic activity biological_process "Any process that stops or reduces the activity of an enzyme." [GOC:jl, GOC:tb] EOG83FKBQ GO:0005737 1/88 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684]