EOG84BDH5 GO:0004407 18/102 histone deacetylase activity molecular_function "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes." [EC:3.5.1.98, PMID:9893272] EOG84BDH5 GO:0000118 18/102 histone deacetylase complex cellular_component "A protein complex that possesses histone deacetylase activity." [GOC:mah] EOG84BDH5 GO:0016787 6/102 hydrolase activity molecular_function "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [ISBN:0198506732] EOG84BDH5 GO:0006355 1/102 regulation of transcription, DNA-templated biological_process "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG84BDH5 GO:0005634 1/102 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG84BDH5 GO:0016575 1/102 histone deacetylation biological_process "The modification of histones by removal of acetyl groups." [GOC:ai] EOG84BDH5 GO:0005737 1/102 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684]