EOG84TRP6	GO:0005524	25/88	ATP binding	molecular_function	"Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732]
EOG84TRP6	GO:0043141	25/88	ATP-dependent 5'-3' DNA helicase activity	molecular_function	"Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'." [GOC:jl]
EOG84TRP6	GO:0035267	3/88	NuA4 histone acetyltransferase complex	cellular_component	"A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60)." [GOC:ecd, PMID:10966108, PMID:14966270]
EOG84TRP6	GO:0031011	3/88	Ino80 complex	cellular_component	"A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity and 3' to 5' DNA helicase activity." [GOC:jh, GOC:rb, PMID:19355820]
EOG84TRP6	GO:0043486	3/88	histone exchange	biological_process	"The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits." [GOC:jl, PMID:11735001, PMID:15066277]
EOG84TRP6	GO:0042127	3/88	regulation of cell proliferation	biological_process	"Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl]
EOG84TRP6	GO:0016573	3/88	histone acetylation	biological_process	"The modification of a histone by the addition of an acetyl group." [GOC:ai]
EOG84TRP6	GO:0003714	3/88	transcription corepressor activity	molecular_function	"Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery." [GOC:txnOH, PMID:10213677, PMID:16858867]
EOG84TRP6	GO:0030111	3/88	regulation of Wnt signaling pathway	biological_process	"Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway." [GOC:dph, GOC:mah, GOC:tb]
EOG84TRP6	GO:0006281	3/88	DNA repair	biological_process	"The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway." [PMID:11563486]
EOG84TRP6	GO:0006351	3/88	transcription, DNA-templated	biological_process	"The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH]
EOG84TRP6	GO:0006355	2/88	regulation of transcription, DNA-templated	biological_process	"Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH]
EOG84TRP6	GO:0034773	1/88	histone H4-K20 trimethylation	biological_process	"The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone." [GOC:mah]
EOG84TRP6	GO:0035102	1/88	PRC1 complex	cellular_component	"A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling." [GOC:bf, PMID:10412979]
EOG84TRP6	GO:0042799	1/88	histone methyltransferase activity (H4-K20 specific)	molecular_function	"Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein." [PMID:12086618]
EOG84TRP6	GO:0010629	1/88	negative regulation of gene expression	biological_process	"Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb]
EOG84TRP6	GO:0000123	1/88	histone acetyltransferase complex	cellular_component	"A protein complex that possesses histone acetyltransferase activity." [GOC:mah]
EOG84TRP6	GO:0005875	1/88	microtubule associated complex	cellular_component	"Any multimeric complex connected to a microtubule." [GOC:jl]
EOG84TRP6	GO:0006342	1/88	chromatin silencing	biological_process	"Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin." [GOC:mah, PMID:10219245]
EOG84TRP6	GO:0005634	1/88	nucleus	cellular_component	"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators]
EOG84TRP6	GO:0005515	1/88	protein binding	molecular_function	"Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators]
EOG84TRP6	GO:0022008	1/88	neurogenesis	biological_process	"Generation of cells within the nervous system." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid, GOC:mtg_15jun06]
EOG84TRP6	GO:0007095	1/88	mitotic G2 DNA damage checkpoint	biological_process	"A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage." [GOC:mtg_cell_cycle]