EOG84XMZ1 GO:0006098 5/37 pentose-phosphate shunt biological_process "The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses." [ISBN:0198506732, MetaCyc:PENTOSE-P-PWY] EOG84XMZ1 GO:0004616 5/37 phosphogluconate dehydrogenase (decarboxylating) activity molecular_function "Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+." [EC:1.1.1.44] EOG84XMZ1 GO:0008442 2/37 3-hydroxyisobutyrate dehydrogenase activity molecular_function "Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+." [EC:1.1.1.31] EOG84XMZ1 GO:0006573 2/37 valine metabolic process biological_process "The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid." [GOC:ai]