EOG87DCW3 GO:0005615 1/13 extracellular space cellular_component "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] EOG87DCW3 GO:0008589 1/13 regulation of smoothened signaling pathway biological_process "Any process that modulates the frequency, rate or extent of smoothened signaling." [GOC:go_curators] EOG87DCW3 GO:0016021 1/13 integral component of membrane cellular_component "The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators]