EOG898XFG GO:0005874 4/30 microtubule cellular_component "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568] EOG898XFG GO:0005525 4/30 GTP binding molecular_function "Interacting selectively and non-covalently with GTP, guanosine triphosphate." [GOC:ai] EOG898XFG GO:0051258 4/30 protein polymerization biological_process "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." [GOC:ai] EOG898XFG GO:0007017 4/30 microtubule-based process biological_process "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." [GOC:mah] EOG898XFG GO:0003924 4/30 GTPase activity molecular_function "Catalysis of the reaction: GTP + H2O = GDP + phosphate." [ISBN:0198547684] EOG898XFG GO:0005200 4/30 structural constituent of cytoskeleton molecular_function "The action of a molecule that contributes to the structural integrity of a cytoskeletal structure." [GOC:mah] EOG898XFG GO:0003682 1/30 chromatin binding molecular_function "Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:jl, ISBN:0198506732, PMID:20404130] EOG898XFG GO:0003677 1/30 DNA binding molecular_function "Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid)." [GOC:dph, GOC:jl, GOC:tb, GOC:vw]