EOG8BCH23 GO:0005852 26/89 eukaryotic translation initiation factor 3 complex cellular_component "A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532] EOG8BCH23 GO:0003743 26/89 translation initiation factor activity molecular_function "Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide." [ISBN:0198506732] EOG8BCH23 GO:0016282 25/89 eukaryotic 43S preinitiation complex cellular_component "A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA." [GOC:hjd, PMID:15145049] EOG8BCH23 GO:0033290 25/89 eukaryotic 48S preinitiation complex cellular_component "A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA." [GOC:hjd, PMID:15145049] EOG8BCH23 GO:0001731 25/89 formation of translation preinitiation complex biological_process "The joining of the small ribosomal subunit, ternary complex, and mRNA." [GOC:hjd] EOG8BCH23 GO:0006446 25/89 regulation of translational initiation biological_process "Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators] EOG8BCH23 GO:0048812 1/89 neuron projection morphogenesis biological_process "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." [GOC:mah]