EOG8BK7MJ	GO:0005852	26/88	eukaryotic translation initiation factor 3 complex	cellular_component	"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532]
EOG8BK7MJ	GO:0003743	26/88	translation initiation factor activity	molecular_function	"Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide." [ISBN:0198506732]
EOG8BK7MJ	GO:0006446	22/88	regulation of translational initiation	biological_process	"Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators]
EOG8BK7MJ	GO:0001731	22/88	formation of translation preinitiation complex	biological_process	"The joining of the small ribosomal subunit, ternary complex, and mRNA." [GOC:hjd]
EOG8BK7MJ	GO:0016282	22/88	eukaryotic 43S preinitiation complex	cellular_component	"A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA." [GOC:hjd, PMID:15145049]
EOG8BK7MJ	GO:0033290	22/88	eukaryotic 48S preinitiation complex	cellular_component	"A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA." [GOC:hjd, PMID:15145049]
EOG8BK7MJ	GO:0022008	1/88	neurogenesis	biological_process	"Generation of cells within the nervous system." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid, GOC:mtg_15jun06]
EOG8BK7MJ	GO:0006413	1/88	translational initiation	biological_process	"The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA." [ISBN:019879276X]
EOG8BK7MJ	GO:0005515	1/88	protein binding	molecular_function	"Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators]