EOG8C8B6K GO:0005576 28/94 extracellular region cellular_component "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GOC:go_curators] EOG8C8B6K GO:0040007 27/94 growth biological_process "The increase in size or mass of an entire organism, a part of an organism or a cell." [GOC:bf, GOC:ma] EOG8C8B6K GO:0007275 2/94 multicellular organismal development biological_process "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] EOG8C8B6K GO:0030154 2/94 cell differentiation biological_process "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] EOG8C8B6K GO:0048100 1/94 wing disc anterior/posterior pattern formation biological_process "The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing." [GOC:jid, PMID:10625531] EOG8C8B6K GO:0046982 1/94 protein heterodimerization activity molecular_function "Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer." [GOC:ai] EOG8C8B6K GO:0007444 1/94 imaginal disc development biological_process "The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.)." [GOC:bf, ISBN:0879694238] EOG8C8B6K GO:0045570 1/94 regulation of imaginal disc growth biological_process "Any process that modulates the frequency, rate or extent of the growth of the imaginal disc." [GOC:go_curators] EOG8C8B6K GO:0016015 1/94 morphogen activity molecular_function "Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient." [GOC:go_curators] EOG8C8B6K GO:0007446 1/94 imaginal disc growth biological_process "The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form." [GOC:bf, GOC:jid, PMID:10679387] EOG8C8B6K GO:0045595 1/94 regulation of cell differentiation biological_process "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators] EOG8C8B6K GO:0046620 1/94 regulation of organ growth biological_process "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] EOG8C8B6K GO:0048066 1/94 developmental pigmentation biological_process "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." [ISBN:0582227089] EOG8C8B6K GO:0048636 1/94 positive regulation of muscle organ development biological_process "Any process that activates, maintains or increases the rate of muscle development." [GOC:go_curators] EOG8C8B6K GO:0007354 1/94 zygotic determination of anterior/posterior axis, embryo biological_process "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] EOG8C8B6K GO:0007516 1/94 hemocyte development biological_process "The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen." [GOC:bf, GOC:mtg_sensu] EOG8C8B6K GO:0007507 1/94 heart development biological_process "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948] EOG8C8B6K GO:0007476 1/94 imaginal disc-derived wing morphogenesis biological_process "The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying." [GOC:bf, GOC:mtg_sensu] EOG8C8B6K GO:0007378 1/94 amnioserosa formation biological_process "Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift." [ISBN:08795694238] EOG8C8B6K GO:0007424 1/94 open tracheal system development biological_process "The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:8625828] EOG8C8B6K GO:0008586 1/94 imaginal disc-derived wing vein morphogenesis biological_process "The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized." [GOC:mtg_sensu] EOG8C8B6K GO:0035222 1/94 wing disc pattern formation biological_process "The process giving rise to the pattern of cell differentiation in the wing imaginal disc." [GOC:bf] EOG8C8B6K GO:0019827 1/94 stem cell population maintenance biological_process "The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types." [GOC:mah, ISBN:0878932437] EOG8C8B6K GO:0007398 1/94 ectoderm development biological_process "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." [GOC:dph, GOC:tb] EOG8C8B6K GO:0001715 1/94 ectodermal cell fate specification biological_process "The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:go_curators] EOG8C8B6K GO:0017145 1/94 stem cell division biological_process "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." [GOC:jid, ISBN:0582227089] EOG8C8B6K GO:0048477 1/94 oogenesis biological_process "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr] EOG8C8B6K GO:0061327 1/94 anterior Malpighian tubule development biological_process "The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] EOG8C8B6K GO:0035168 1/94 larval lymph gland hemocyte differentiation biological_process "The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu, PMID:14602069] EOG8C8B6K GO:0007313 1/94 maternal specification of dorsal/ventral axis, oocyte, soma encoded biological_process "Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238] EOG8C8B6K GO:0001708 1/94 cell fate specification biological_process "The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:go_curators] EOG8C8B6K GO:0001745 1/94 compound eye morphogenesis biological_process "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu] EOG8C8B6K GO:0048619 1/94 embryonic hindgut morphogenesis biological_process "The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase." [GOC:jid, GOC:rc] EOG8C8B6K GO:0035147 1/94 branch fusion, open tracheal system biological_process "Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint." [GOC:mtg_sensu, PMID:14570584] EOG8C8B6K GO:0008360 1/94 regulation of cell shape biological_process "Any process that modulates the surface configuration of a cell." [GOC:dph, GOC:go_curators, GOC:tb] EOG8C8B6K GO:0007443 1/94 Malpighian tubule morphogenesis biological_process "The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut." [GOC:bf, ISBN:0582227089] EOG8C8B6K GO:0008285 1/94 negative regulation of cell proliferation biological_process "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators] EOG8C8B6K GO:0007455 1/94 eye-antennal disc morphogenesis biological_process "The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps." [GOC:bf, ISBN:0879694238] EOG8C8B6K GO:0035214 1/94 eye-antennal disc development biological_process "Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps." [GOC:bf, ISBN:0879694238] EOG8C8B6K GO:0007425 1/94 epithelial cell fate determination, open tracheal system biological_process "The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11063940] EOG8C8B6K GO:0007281 1/94 germ cell development biological_process "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." [GOC:go_curators] EOG8C8B6K GO:0035158 1/94 regulation of tube diameter, open tracheal system biological_process "Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size." [GOC:mtg_sensu, PMID:14570584] EOG8C8B6K GO:0030718 1/94 germ-line stem cell population maintenance biological_process "Any process by which an organism or tissue maintains a population of germ-line stem cells." [ISBN:0879694238] EOG8C8B6K GO:0007450 1/94 dorsal/ventral pattern formation, imaginal disc biological_process "The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed." [GOC:jid, ISBN:0879694238] EOG8C8B6K GO:0035309 1/94 wing and notum subfield formation biological_process "The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures." [PMID:10860999] EOG8C8B6K GO:0030509 1/94 BMP signaling pathway biological_process "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, ISBN:0878932437, PR:000000034] EOG8C8B6K GO:0010629 1/94 negative regulation of gene expression biological_process "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] EOG8C8B6K GO:0035263 1/94 genital disc sexually dimorphic development biological_process "The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed." [PMID:11290302, PMID:11494318, PMID:11702781] EOG8C8B6K GO:0007304 1/94 chorion-containing eggshell formation biological_process "The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster." [GOC:mah, GOC:mtg_sensu] EOG8C8B6K GO:0007427 1/94 epithelial cell migration, open tracheal system biological_process "The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu] EOG8C8B6K GO:0001709 1/94 cell fate determination biological_process "A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [ISBN:0878932437] EOG8C8B6K GO:0061353 1/94 BMP signaling pathway involved in Malpighian tubule cell chemotaxis biological_process "A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule." [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135] EOG8C8B6K GO:0007458 1/94 progression of morphogenetic furrow involved in compound eye morphogenesis biological_process "The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc." [PMID:3076112, PMID:3937883] EOG8C8B6K GO:0046845 1/94 branched duct epithelial cell fate determination, open tracheal system biological_process "Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode." [GOC:mtg_sensu, PMID:10684581] EOG8C8B6K GO:0061320 1/94 pericardial nephrocyte differentiation biological_process "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [CL:0000474, GOC:dph, GOC:mtg_kidney_jan10, GOC:sart, PMID:19783135] EOG8C8B6K GO:0007498 1/94 mesoderm development biological_process "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb] EOG8C8B6K GO:0005515 1/94 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] EOG8C8B6K GO:0035156 1/94 fusion cell fate specification biological_process "The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion." [PMID:11063940] EOG8C8B6K GO:0030707 1/94 ovarian follicle cell development biological_process "The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:10822261] EOG8C8B6K GO:0007440 1/94 foregut morphogenesis biological_process "The process in which the anatomical structures of the foregut are generated and organized." [GOC:jid] EOG8C8B6K GO:0007479 1/94 leg disc proximal/distal pattern formation biological_process "The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg." [GOC:bf] EOG8C8B6K GO:0035215 1/94 genital disc development biological_process "Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia." [GOC:bf, ISBN:0879694238, PMID:11494318] EOG8C8B6K GO:0005622 1/94 intracellular cellular_component "The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] EOG8C8B6K GO:0009948 1/94 anterior/posterior axis specification biological_process "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:tb] EOG8C8B6K GO:0007423 1/94 sensory organ development biological_process "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." [GOC:go_curators] EOG8C8B6K GO:0007393 1/94 dorsal closure, leading edge cell fate determination biological_process "The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:bf, GOC:go_curators, PMID:12147138] EOG8C8B6K GO:0007447 1/94 imaginal disc pattern formation biological_process "The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form." [GOC:dph, GOC:isa_complete, GOC:jid] EOG8C8B6K GO:0007474 1/94 imaginal disc-derived wing vein specification biological_process "The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified." [GOC:dph, GOC:isa_complete, GOC:mtg_sensu] EOG8C8B6K GO:0009950 1/94 dorsal/ventral axis specification biological_process "The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:go_curators, GOC:tb] EOG8C8B6K GO:0005160 1/94 transforming growth factor beta receptor binding molecular_function "Interacting selectively and non-covalently with the transforming growth factor beta receptor." [GOC:ai] EOG8C8B6K GO:0042803 1/94 protein homodimerization activity molecular_function "Interacting selectively and non-covalently with an identical protein to form a homodimer." [GOC:jl] EOG8C8B6K GO:0042127 1/94 regulation of cell proliferation biological_process "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl] EOG8C8B6K GO:0005518 1/94 collagen binding molecular_function "Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:ai, ISBN:0198506732] EOG8C8B6K GO:0048542 1/94 lymph gland development biological_process "The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages." [GOC:mtg_sensu, GOC:rc] EOG8C8B6K GO:0008201 1/94 heparin binding molecular_function "Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues." [GOC:jl, ISBN:0198506732] EOG8C8B6K GO:0007442 1/94 hindgut morphogenesis biological_process "The process in which the anatomical structures of the hindgut are generated and organized." [GOC:jid] EOG8C8B6K GO:0042078 1/94 germ-line stem cell division biological_process "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." [GOC:jid, PMID:2279698] EOG8C8B6K GO:0046843 1/94 dorsal appendage formation biological_process "Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration." [ISBN:0879694238] EOG8C8B6K GO:0005615 1/94 extracellular space cellular_component "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] EOG8C8B6K GO:0035217 1/94 labial disc development biological_process "Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis." [GOC:bf, ISBN:0879694238] EOG8C8B6K GO:0035224 1/94 genital disc anterior/posterior pattern formation biological_process "The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium)." [PMID:11494318] EOG8C8B6K GO:0007473 1/94 wing disc proximal/distal pattern formation biological_process "The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing." [GOC:bf] EOG8C8B6K GO:0007352 1/94 zygotic specification of dorsal/ventral axis biological_process "The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote." [GOC:bf] EOG8C8B6K GO:0010002 1/94 cardioblast differentiation biological_process "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] EOG8C8B6K GO:0007179 1/94 transforming growth factor beta receptor signaling pathway biological_process "A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:BHF, GOC:mah, GOC:signaling] EOG8C8B6K GO:0007448 1/94 anterior/posterior pattern specification, imaginal disc biological_process "The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form." [GOC:bf, ISBN:0879694238] EOG8C8B6K GO:0007391 1/94 dorsal closure biological_process "The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally." [PMID:9224720] EOG8C8B6K GO:0045705 1/94 negative regulation of salivary gland boundary specification biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination." [GOC:go_curators, GOC:tb]