EOG8CJXXD GO:0005634 28/85 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8CJXXD GO:0006355 28/85 regulation of transcription, DNA-templated biological_process "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG8CJXXD GO:0003677 28/85 DNA binding molecular_function "Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid)." [GOC:dph, GOC:jl, GOC:tb, GOC:vw] EOG8CJXXD GO:0007275 27/85 multicellular organismal development biological_process "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] EOG8CJXXD GO:0007405 1/85 neuroblast proliferation biological_process "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." [GOC:ai, GOC:mtg_sensu, GOC:sart] EOG8CJXXD GO:0000122 1/85 negative regulation of transcription from RNA polymerase II promoter biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH] EOG8CJXXD GO:0010001 1/85 glial cell differentiation biological_process "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell." [GOC:go_curators, GOC:mtg_sensu] EOG8CJXXD GO:0045179 1/85 apical cortex cellular_component "The region that lies just beneath the plasma membrane on the apical edge of a cell." [GOC:bf] EOG8CJXXD GO:0003700 1/85 transcription factor activity, sequence-specific DNA binding molecular_function "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex." [GOC:curators, GOC:txnOH] EOG8CJXXD GO:0045178 1/85 basal part of cell cellular_component "The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue." [GOC:mah, ISBN:0185316194] EOG8CJXXD GO:0005886 1/85 plasma membrane cellular_component "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] EOG8CJXXD GO:0005938 1/85 cell cortex cellular_component "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194] EOG8CJXXD GO:0010628 1/85 positive regulation of gene expression biological_process "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] EOG8CJXXD GO:0007422 1/85 peripheral nervous system development biological_process "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GOC:go_curators, UBERON:0000010] EOG8CJXXD GO:0045165 1/85 cell fate commitment biological_process "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [ISBN:0716731185] EOG8CJXXD GO:0042676 1/85 compound eye cone cell fate commitment biological_process "The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type." [GOC:mtg_sensu] EOG8CJXXD GO:0007402 1/85 ganglion mother cell fate determination biological_process "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators] EOG8CJXXD GO:0010629 1/85 negative regulation of gene expression biological_process "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb] EOG8CJXXD GO:0007423 1/85 sensory organ development biological_process "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." [GOC:go_curators] EOG8CJXXD GO:0007416 1/85 synapse assembly biological_process "The aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:mah] EOG8CJXXD GO:0001754 1/85 eye photoreceptor cell differentiation biological_process "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." [GOC:go_curators] EOG8CJXXD GO:0007619 1/85 courtship behavior biological_process "The behavioral interactions between organisms for the purpose of attracting sexual partners." [GOC:ai, GOC:dph] EOG8CJXXD GO:0050771 1/85 negative regulation of axonogenesis biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis." [GOC:ai] EOG8CJXXD GO:0007417 1/85 central nervous system development biological_process "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GOC:bf, GOC:jid, ISBN:0582227089] EOG8CJXXD GO:0008104 1/85 protein localization biological_process "Any process in which a protein is transported to, or maintained in, a specific location." [GOC:ai] EOG8CJXXD GO:0007409 1/85 axonogenesis biological_process "De novo generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells. Refers to the morphogenesis or creation of shape or form of the developing axon." [GOC:dph, GOC:jid, GOC:pg, GOC:pr, ISBN:0198506732] EOG8CJXXD GO:0045664 1/85 regulation of neuron differentiation biological_process "Any process that modulates the frequency, rate or extent of neuron differentiation." [GOC:go_curators] EOG8CJXXD GO:0042673 1/85 regulation of retinal cone cell fate specification biological_process "Any process that mediates the specification of a cell into a retinal cone cell." [GOC:go_curators] EOG8CJXXD GO:0048813 1/85 dendrite morphogenesis biological_process "The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell." [GOC:jl, ISBN:0198506732] EOG8CJXXD GO:0008049 1/85 male courtship behavior biological_process "The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster." [GOC:mtg_sensu, GOC:pr] EOG8CJXXD GO:0007420 1/85 brain development biological_process "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955] EOG8CJXXD GO:0007406 1/85 negative regulation of neuroblast proliferation biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts." [GOC:ai] EOG8CJXXD GO:0005875 1/85 microtubule associated complex cellular_component "Any multimeric complex connected to a microtubule." [GOC:jl] EOG8CJXXD GO:0007419 1/85 ventral cord development biological_process "The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms." [GOC:bf, GOC:go_curators, http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/Spemann.html] EOG8CJXXD GO:0001708 1/85 cell fate specification biological_process "The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment." [GOC:go_curators] EOG8CJXXD GO:0045676 1/85 regulation of R7 cell differentiation biological_process "Any process that modulates the frequency, rate or extent of R7 differentiation." [GOC:go_curators] EOG8CJXXD GO:0008356 1/85 asymmetric cell division biological_process "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519] EOG8CJXXD GO:0006909 1/85 phagocytosis biological_process "An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." [ISBN:0198506732] EOG8CJXXD GO:0055059 1/85 asymmetric neuroblast division biological_process "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." [GOC:dph] EOG8CJXXD GO:0045180 1/85 basal cortex cellular_component "The region that lies just beneath the plasma membrane on the basal edge of a cell." [GOC:bf] EOG8CJXXD GO:0007399 1/85 nervous system development biological_process "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." [GOC:dgh] EOG8CJXXD GO:0007465 1/85 R7 cell fate commitment biological_process "The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium." [PMID:3076112, PMID:3937883] EOG8CJXXD GO:0007411 1/85 axon guidance biological_process "The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues." [ISBN:0878932437] EOG8CJXXD GO:0006351 1/85 transcription, DNA-templated biological_process "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH] EOG8CJXXD GO:0007400 1/85 neuroblast fate determination biological_process "The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus." [GOC:go_curators] EOG8CJXXD GO:0055060 1/85 asymmetric neuroblast division resulting in ganglion mother cell formation biological_process "Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell." [GOC:dph] EOG8CJXXD GO:0050909 1/85 sensory perception of taste biological_process "The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process." [GOC:ai, http://www.onelook.com/] EOG8CJXXD GO:0060385 1/85 axonogenesis involved in innervation biological_process "The neurite development process that generates a long process of a neuron, as it invades a target tissue." [GOC:dph, GOC:sart] EOG8CJXXD GO:0070983 1/85 dendrite guidance biological_process "The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues." [GOC:sart, PMID:15046878] EOG8CJXXD GO:0008285 1/85 negative regulation of cell proliferation biological_process "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators] EOG8CJXXD GO:1900180 1/85 regulation of protein localization to nucleus biological_process "Any process that modulates the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] EOG8CJXXD GO:0001078 1/85 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding molecular_function "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:txnOH]