EOG8D2945 GO:0004502 20/94 kynurenine 3-monooxygenase activity molecular_function "Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+)." [EC:1.14.13.9, RHEA:20548] EOG8D2945 GO:0016021 19/94 integral component of membrane cellular_component "The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators] EOG8D2945 GO:0043420 19/94 anthranilate metabolic process biological_process "The chemical reactions and pathways involving anthranilate (2-aminobenzoate)." [CHEBI:16567, GOC:jl] EOG8D2945 GO:0034354 19/94 'de novo' NAD biosynthetic process from tryptophan biological_process "The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH." [PMID:17161604] EOG8D2945 GO:0006569 19/94 tryptophan catabolic process biological_process "The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid." [ISBN:0198547684] EOG8D2945 GO:0050660 19/94 flavin adenine dinucleotide binding molecular_function "Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2." [CHEBI:24040, GOC:ai, GOC:imk, ISBN:0198506732] EOG8D2945 GO:0019805 19/94 quinolinate biosynthetic process biological_process "The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid." [GOC:ai] EOG8D2945 GO:0031966 16/94 mitochondrial membrane cellular_component "Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." [GOC:mah, NIF_Subcellular:sao1045389829] EOG8D2945 GO:0019674 3/94 NAD metabolic process biological_process "The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid." [GOC:jl, ISBN:0618254153] EOG8D2945 GO:0005741 3/94 mitochondrial outer membrane cellular_component "The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope." [GOC:ai] EOG8D2945 GO:0016491 2/94 oxidoreductase activity molecular_function "Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced." [GOC:go_curators] EOG8D2945 GO:0004497 1/94 monooxygenase activity molecular_function "Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water." [http://www.onelook.com/, ISBN:0198506732] EOG8D2945 GO:0006727 1/94 ommochrome biosynthetic process biological_process "The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye." [ISBN:0198506732] EOG8D2945 GO:0048072 1/94 compound eye pigmentation biological_process "Establishment of a pattern of pigment in the compound eye." [GOC:jid] EOG8D2945 GO:0070189 1/94 kynurenine metabolic process biological_process "The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine." [CHEBI:28683, GOC:mah, GOC:rph] EOG8D2945 GO:1901216 1/94 positive regulation of neuron death biological_process "Any process that activates or increases the frequency, rate or extent of neuron death." [GOC:rph, GOC:TermGenie]