EOG8D55BM GO:0005634 5/89 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8D55BM GO:0008286 5/89 insulin receptor signaling pathway biological_process "The series of molecular signals generated as a consequence of the insulin receptor binding to insulin." [GOC:ceb] EOG8D55BM GO:0005159 5/89 insulin-like growth factor receptor binding molecular_function "Interacting selectively and non-covalently with the insulin-like growth factor receptor." [GOC:jl] EOG8D55BM GO:0005737 5/89 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG8D55BM GO:0043231 5/89 intracellular membrane-bounded organelle cellular_component "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] EOG8D55BM GO:0010259 5/89 multicellular organismal aging biological_process "An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700)." [GOC:PO_curators] EOG8D55BM GO:0048009 5/89 insulin-like growth factor receptor signaling pathway biological_process "The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands." [GOC:ceb] EOG8D55BM GO:0005158 5/89 insulin receptor binding molecular_function "Interacting selectively and non-covalently with the insulin receptor." [GOC:ai] EOG8D55BM GO:0007296 5/89 vitellogenesis biological_process "The production of yolk. Yolk is a mixture of materials used for embryonic nutrition." [GOC:dph, ISBN:0879694238] EOG8D55BM GO:0048477 4/89 oogenesis biological_process "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr] EOG8D55BM GO:0040008 4/89 regulation of growth biological_process "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." [GOC:ems, GOC:mah] EOG8D55BM GO:0060250 1/89 germ-line stem-cell niche homeostasis biological_process "A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion." [GOC:dph] EOG8D55BM GO:0042594 1/89 response to starvation biological_process "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment." [GOC:go_curators] EOG8D55BM GO:0007285 1/89 primary spermatocyte growth biological_process "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." [GOC:jid, ISBN:0879694238] EOG8D55BM GO:0008355 1/89 olfactory learning biological_process "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue." [ISBN:0582227089] EOG8D55BM GO:0007295 1/89 growth of a germarium-derived egg chamber biological_process "Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] EOG8D55BM GO:0040014 1/89 regulation of multicellular organism growth biological_process "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." [GOC:dph, GOC:ems, GOC:tb] EOG8D55BM GO:0000902 1/89 cell morphogenesis biological_process "The developmental process in which the size or shape of a cell is generated and organized." [GOC:clt, GOC:dph, GOC:go_curators, GOC:tb] EOG8D55BM GO:0007568 1/89 aging biological_process "A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700)." [GOC:PO_curators] EOG8D55BM GO:0045793 1/89 positive regulation of cell size biological_process "Any process that increases cell size." [GOC:go_curators] EOG8D55BM GO:0034059 1/89 response to anoxia biological_process "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%." [GOC:kmv] EOG8D55BM GO:0048133 1/89 male germ-line stem cell asymmetric division biological_process "The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes." [GOC:jid] EOG8D55BM GO:0046620 1/89 regulation of organ growth biological_process "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] EOG8D55BM GO:0030307 1/89 positive regulation of cell growth biological_process "Any process that activates or increases the frequency, rate, extent or direction of cell growth." [GOC:go_curators] EOG8D55BM GO:0005515 1/89 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] EOG8D55BM GO:0042169 1/89 SH2 domain binding molecular_function "Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class." [GOC:go_curators, Pfam:PF00017] EOG8D55BM GO:0008340 1/89 determination of adult lifespan biological_process "The control of viability and duration in the adult phase of the life-cycle." [GOC:ems] EOG8D55BM GO:0046622 1/89 positive regulation of organ growth biological_process "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] EOG8D55BM GO:0008361 1/89 regulation of cell size biological_process "Any process that modulates the size of a cell." [GOC:go_curators] EOG8D55BM GO:0008152 1/89 metabolic process biological_process "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] EOG8D55BM GO:0005829 1/89 cytosol cellular_component "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." [GOC:hjd, GOC:jl] EOG8D55BM GO:0050778 1/89 positive regulation of immune response biological_process "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] EOG8D55BM GO:0043548 1/89 phosphatidylinositol 3-kinase binding molecular_function "Interacting selectively and non-covalently with a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring." [PMID:10209156, PMID:9255069] EOG8D55BM GO:0035159 1/89 regulation of tube length, open tracheal system biological_process "Ensuring that a tube in an open tracheal system is of the correct length." [GOC:bf, GOC:mtg_sensu] EOG8D55BM GO:0040018 1/89 positive regulation of multicellular organism growth biological_process "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:go_curators, GOC:tb]