EOG8FTZDK GO:0018024 25/104 histone-lysine N-methyltransferase activity molecular_function "Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives." [EC:2.1.1.43, RESID:AA0074, RESID:AA0075, RESID:AA0076] EOG8FTZDK GO:0005634 25/104 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8FTZDK GO:0006348 1/104 chromatin silencing at telomere biological_process "Repression of transcription of telomeric DNA by altering the structure of chromatin." [PMID:10219245] EOG8FTZDK GO:0006342 1/104 chromatin silencing biological_process "Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin." [GOC:mah, PMID:10219245] EOG8FTZDK GO:0048096 1/104 chromatin-mediated maintenance of transcription biological_process "Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable." [GOC:jid] EOG8FTZDK GO:0034729 1/104 histone H3-K79 methylation biological_process "The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone." [GOC:se] EOG8FTZDK GO:0016571 1/104 histone methylation biological_process "The modification of histones by addition of methyl groups." [GOC:ai] EOG8FTZDK GO:0046331 1/104 lateral inhibition biological_process "Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells." [GOC:bf, GOC:kmv] EOG8FTZDK GO:2000637 1/104 positive regulation of gene silencing by miRNA biological_process "Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA." [GOC:dph] EOG8FTZDK GO:0031151 1/104 histone methyltransferase activity (H3-K79 specific) molecular_function "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein." [GOC:mah, PMID:15371351] EOG8FTZDK GO:0035097 1/104 histone methyltransferase complex cellular_component "A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins." [GOC:bf]