EOG8GXJ1Z GO:0005506 14/91 iron ion binding molecular_function "Interacting selectively and non-covalently with iron (Fe) ions." [GOC:ai] EOG8GXJ1Z GO:0032453 14/91 histone demethylase activity (H3-K4 specific) molecular_function "Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein." [GOC:mah] EOG8GXJ1Z GO:0005634 14/91 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8GXJ1Z GO:0016706 14/91 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors molecular_function "Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor." [GOC:mah] EOG8GXJ1Z GO:0045892 14/91 negative regulation of transcription, DNA-templated biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG8GXJ1Z GO:0006351 14/91 transcription, DNA-templated biological_process "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH] EOG8GXJ1Z GO:0070544 14/91 histone H3-K36 demethylation biological_process "The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone." [GOC:sart, PMID:19061644] EOG8GXJ1Z GO:0051864 14/91 histone demethylase activity (H3-K36 specific) molecular_function "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein." [PMID:16362057] EOG8GXJ1Z GO:0034720 14/91 histone H3-K4 demethylation biological_process "The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone." [GOC:mah]