EOG8J6V56 GO:0043161 1/92 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process "The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome." [GOC:go_curators] EOG8J6V56 GO:0006289 1/92 nucleotide-excision repair biological_process "A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts)." [PMID:10197977] EOG8J6V56 GO:0003684 1/92 damaged DNA binding molecular_function "Interacting selectively and non-covalently with damaged DNA." [GOC:jl] EOG8J6V56 GO:0070628 1/92 proteasome binding molecular_function "Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation." [GOC:mah] EOG8J6V56 GO:0042982 1/92 amyloid precursor protein metabolic process biological_process "The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease." [GOC:go_curators] EOG8J6V56 GO:0005515 1/92 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators]