EOG8MGVN9	GO:0020037	24/99	heme binding	molecular_function	"Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring." [CHEBI:30413, GOC:ai]
EOG8MGVN9	GO:0004383	24/99	guanylate cyclase activity	molecular_function	"Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate." [EC:4.6.1.2]
EOG8MGVN9	GO:0035556	23/99	intracellular signal transduction	biological_process	"The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782]
EOG8MGVN9	GO:0000166	22/99	nucleotide binding	molecular_function	"Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose." [GOC:mah, ISBN:0198547684]
EOG8MGVN9	GO:0016021	2/99	integral component of membrane	cellular_component	"The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane." [GOC:dos, GOC:go_curators]
EOG8MGVN9	GO:0008074	1/99	guanylate cyclase complex, soluble	cellular_component	"Complex that possesses guanylate cyclase activity and is not bound to a membrane." [GOC:mah]
EOG8MGVN9	GO:0046872	1/99	metal ion binding	molecular_function	"Interacting selectively and non-covalently with any metal ion." [GOC:ai]
EOG8MGVN9	GO:0005525	1/99	GTP binding	molecular_function	"Interacting selectively and non-covalently with GTP, guanosine triphosphate." [GOC:ai]
EOG8MGVN9	GO:0019826	1/99	oxygen sensor activity	molecular_function	"Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2)." [GOC:mah]
EOG8MGVN9	GO:0000302	1/99	response to reactive oxygen species	biological_process	"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." [GOC:krc]
EOG8MGVN9	GO:0019825	1/99	oxygen binding	molecular_function	"Interacting selectively and non-covalently with oxygen (O2)." [GOC:jl]
EOG8MGVN9	GO:0070026	1/99	nitric oxide binding	molecular_function	"Interacting selectively and non-covalently with nitric oxide (NO)." [GOC:ecd]
EOG8MGVN9	GO:0046982	1/99	protein heterodimerization activity	molecular_function	"Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer." [GOC:ai]
EOG8MGVN9	GO:0042803	1/99	protein homodimerization activity	molecular_function	"Interacting selectively and non-covalently with an identical protein to form a homodimer." [GOC:jl]
EOG8MGVN9	GO:0001666	1/99	response to hypoxia	biological_process	"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." [GOC:hjd]
EOG8MGVN9	GO:0006184	1/99	obsolete GTP catabolic process	biological_process	"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate." [ISBN:0198506732]
EOG8MGVN9	GO:0070025	1/99	carbon monoxide binding	molecular_function	"Interacting selectively and non-covalently with carbon monoxide (CO)." [GOC:ecd]
EOG8MGVN9	GO:0006182	1/99	cGMP biosynthetic process	biological_process	"The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate." [ISBN:0198506732]