EOG8MGVNH GO:0005634 29/97 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8MGVNH GO:0000978 28/97 RNA polymerase II core promoter proximal region sequence-specific DNA binding molecular_function "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II." [GOC:txnOH] EOG8MGVNH GO:0000982 27/97 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding molecular_function "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II." [GOC:txnOH] EOG8MGVNH GO:0016360 2/97 sensory organ precursor cell fate determination biological_process "The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed." [GOC:go_curators] EOG8MGVNH GO:0007219 2/97 Notch signaling pathway biological_process "A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, GOC:signaling] EOG8MGVNH GO:0003677 2/97 DNA binding molecular_function "Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid)." [GOC:dph, GOC:jl, GOC:tb, GOC:vw] EOG8MGVNH GO:0005737 2/97 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG8MGVNH GO:0030097 1/97 hemopoiesis biological_process "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." [GOC:dgh, ISBN:0198506732] EOG8MGVNH GO:0006355 1/97 regulation of transcription, DNA-templated biological_process "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG8MGVNH GO:0042688 1/97 crystal cell differentiation biological_process "The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph." [GOC:bf, http://sdb.bio.purdue.edu/fly/gene/serpent3.htm] EOG8MGVNH GO:0043565 1/97 sequence-specific DNA binding molecular_function "Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding." [GOC:jl] EOG8MGVNH GO:1900087 1/97 positive regulation of G1/S transition of mitotic cell cycle biological_process "Any cell cycle regulatory process that promotes the commitment of a cell from G1 to S phase of the mitotic cell cycle." [GOC:mtg_cell_cycle] EOG8MGVNH GO:0000122 1/97 negative regulation of transcription from RNA polymerase II promoter biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH] EOG8MGVNH GO:0005515 1/97 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] EOG8MGVNH GO:0045892 1/97 negative regulation of transcription, DNA-templated biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG8MGVNH GO:0017053 1/97 transcriptional repressor complex cellular_component "A protein complex that possesses activity that prevents or downregulates transcription." [GOC:mah] EOG8MGVNH GO:0007616 1/97 long-term memory biological_process "The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation." [http://hebb.mit.edu/courses/9.03/lecture4.html, ISBN:0582227089] EOG8MGVNH GO:0001709 1/97 cell fate determination biological_process "A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment." [ISBN:0878932437] EOG8MGVNH GO:0001077 1/97 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding molecular_function "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter." [GOC:txnOH] EOG8MGVNH GO:0000980 1/97 RNA polymerase II distal enhancer sequence-specific DNA binding molecular_function "Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter." [GOC:txnOH] EOG8MGVNH GO:0043234 1/97 protein complex cellular_component "A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical." [GOC:go_curators, http://www.ebi.ac.uk/intact/complex/documentation/] EOG8MGVNH GO:0008356 1/97 asymmetric cell division biological_process "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519] EOG8MGVNH GO:0046331 1/97 lateral inhibition biological_process "Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells." [GOC:bf, GOC:kmv] EOG8MGVNH GO:0042683 1/97 negative regulation of compound eye cone cell fate specification biological_process "Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell." [GOC:mtg_sensu] EOG8MGVNH GO:0045944 1/97 positive regulation of transcription from RNA polymerase II promoter biological_process "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH] EOG8MGVNH GO:0045893 1/97 positive regulation of transcription, DNA-templated biological_process "Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG8MGVNH GO:0006351 1/97 transcription, DNA-templated biological_process "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH] EOG8MGVNH GO:0007252 1/97 I-kappaB phosphorylation biological_process "The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription." [GOC:bf, GOC:jl, PMID:21772278, PMID:7594468] EOG8MGVNH GO:0008586 1/97 imaginal disc-derived wing vein morphogenesis biological_process "The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized." [GOC:mtg_sensu] EOG8MGVNH GO:0048190 1/97 wing disc dorsal/ventral pattern formation biological_process "The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing." [GOC:jid] EOG8MGVNH GO:0005700 1/97 polytene chromosome cellular_component "A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible." [ISBN:0198506732]