EOG8NW20Q	GO:0005634	42/146	nucleus	cellular_component	"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators]
EOG8NW20Q	GO:0003700	41/146	transcription factor activity, sequence-specific DNA binding	molecular_function	"Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex." [GOC:curators, GOC:txnOH]
EOG8NW20Q	GO:0045944	2/146	positive regulation of transcription from RNA polymerase II promoter	biological_process	"Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH]
EOG8NW20Q	GO:0008063	2/146	Toll signaling pathway	biological_process	"A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:go_curators, PMID:11135568, PMID:19126860]
EOG8NW20Q	GO:0035206	2/146	regulation of hemocyte proliferation	biological_process	"Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster." [GOC:bf, GOC:mtg_sensu]
EOG8NW20Q	GO:0006955	2/146	immune response	biological_process	"Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05]
EOG8NW20Q	GO:0043565	2/146	sequence-specific DNA binding	molecular_function	"Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding." [GOC:jl]
EOG8NW20Q	GO:0006952	2/146	defense response	biological_process	"Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators]
EOG8NW20Q	GO:0001077	2/146	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	molecular_function	"Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter." [GOC:txnOH]
EOG8NW20Q	GO:0006964	2/146	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	biological_process	"Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria." [GOC:mah, PMID:10973475]
EOG8NW20Q	GO:0042387	2/146	plasmatocyte differentiation	biological_process	"The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response." [PMID:11921077, PMID:8174791]
EOG8NW20Q	GO:0005515	2/146	protein binding	molecular_function	"Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators]
EOG8NW20Q	GO:0048935	2/146	peripheral nervous system neuron development	biological_process	"The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GOC:dgh]
EOG8NW20Q	GO:0005737	2/146	cytoplasm	cellular_component	"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684]
EOG8NW20Q	GO:0000381	1/146	regulation of alternative mRNA splicing, via spliceosome	biological_process	"Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs." [GOC:krc]
EOG8NW20Q	GO:0006974	1/146	cellular response to DNA damage stimulus	biological_process	"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism." [GOC:go_curators]
EOG8NW20Q	GO:0007507	1/146	heart development	biological_process	"The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948]
EOG8NW20Q	GO:0006967	1/146	positive regulation of antifungal peptide biosynthetic process	biological_process	"Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis." [GOC:mah]
EOG8NW20Q	GO:0045893	1/146	positive regulation of transcription, DNA-templated	biological_process	"Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH]
EOG8NW20Q	GO:0009953	1/146	dorsal/ventral pattern formation	biological_process	"The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb]
EOG8NW20Q	GO:0010629	1/146	negative regulation of gene expression	biological_process	"Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb]
EOG8NW20Q	GO:0010004	1/146	gastrulation involving germ band extension	biological_process	"A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu]
EOG8NW20Q	GO:0010628	1/146	positive regulation of gene expression	biological_process	"Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." [GOC:dph, GOC:tb]
EOG8NW20Q	GO:0006366	1/146	transcription from RNA polymerase II promoter	biological_process	"The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs)." [GOC:jl, GOC:txnOH, ISBN:0321000382]
EOG8NW20Q	GO:0050830	1/146	defense response to Gram-positive bacterium	biological_process	"Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism." [GOC:ai]
EOG8NW20Q	GO:0007498	1/146	mesoderm development	biological_process	"The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb]
EOG8NW20Q	GO:0035070	1/146	salivary gland histolysis	biological_process	"The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly." [GOC:bf, GOC:dph, PMID:9409683]
EOG8NW20Q	GO:0000122	1/146	negative regulation of transcription from RNA polymerase II promoter	biological_process	"Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter." [GOC:go_curators, GOC:txnOH]
EOG8NW20Q	GO:0007369	1/146	gastrulation	biological_process	"A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:curators, ISBN:9780878933846]
EOG8NW20Q	GO:0008354	1/146	germ cell migration	biological_process	"The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." [GOC:bf, GOC:jl]
EOG8NW20Q	GO:0009952	1/146	anterior/posterior pattern specification	biological_process	"The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb]
EOG8NW20Q	GO:0003677	1/146	DNA binding	molecular_function	"Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid)." [GOC:dph, GOC:jl, GOC:tb, GOC:vw]
EOG8NW20Q	GO:0007501	1/146	mesodermal cell fate specification	biological_process	"The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:go_curators]
EOG8NW20Q	GO:0002781	1/146	antifungal peptide production	biological_process	"The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771]
EOG8NW20Q	GO:0009620	1/146	response to fungus	biological_process	"Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus." [GOC:hb]
EOG8NW20Q	GO:0000977	1/146	RNA polymerase II regulatory region sequence-specific DNA binding	molecular_function	"Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II." [GOC:txnOH]
EOG8NW20Q	GO:0009950	1/146	dorsal/ventral axis specification	biological_process	"The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism." [GOC:dph, GOC:go_curators, GOC:tb]
EOG8NW20Q	GO:0007398	1/146	ectoderm development	biological_process	"The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." [GOC:dph, GOC:tb]
EOG8NW20Q	GO:0070491	1/146	repressing transcription factor binding	molecular_function	"Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription." [GOC:mah, GOC:txnOH]
EOG8NW20Q	GO:0031594	1/146	neuromuscular junction	cellular_component	"The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." [GOC:nln]
EOG8NW20Q	GO:0045087	1/146	innate immune response	biological_process	"Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_15nov05, GOC:mtg_sensu]
EOG8NW20Q	GO:0001715	1/146	ectodermal cell fate specification	biological_process	"The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed." [GOC:go_curators]
EOG8NW20Q	GO:0006355	1/146	regulation of transcription, DNA-templated	biological_process	"Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH]
EOG8NW20Q	GO:0050832	1/146	defense response to fungus	biological_process	"Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." [GOC:ai]
EOG8NW20Q	GO:0007419	1/146	ventral cord development	biological_process	"The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms." [GOC:bf, GOC:go_curators, http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/Spemann.html]
EOG8NW20Q	GO:0070379	1/146	high mobility group box 1 binding	molecular_function	"Interacting selectively and non-covalently with high mobility group box 1 (HMBGB1)." [GOC:add, PMID:18431461]
EOG8NW20Q	GO:0045892	1/146	negative regulation of transcription, DNA-templated	biological_process	"Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH]
EOG8NW20Q	GO:0035006	1/146	melanization defense response	biological_process	"The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin." [GOC:bf, PMID:12408809]
EOG8NW20Q	GO:0035171	1/146	lamellocyte differentiation	biological_process	"The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes." [GOC:bf, PMID:14734104]