EOG8RJJHB GO:0006729 23/84 tetrahydrobiopterin biosynthetic process biological_process "The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine." [CHEBI:15372, GOC:go_curators, ISBN:0198506732] EOG8RJJHB GO:0003874 23/84 6-pyruvoyltetrahydropterin synthase activity molecular_function "Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate." [EC:4.2.3.12, RHEA:22051] EOG8RJJHB GO:0046872 5/84 metal ion binding molecular_function "Interacting selectively and non-covalently with any metal ion." [GOC:ai] EOG8RJJHB GO:0006728 1/84 pteridine biosynthetic process biological_process "The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group." [ISBN:0198506732]