EOG8S7N4H GO:0005524 25/94 ATP binding molecular_function "Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator." [ISBN:0198506732] EOG8S7N4H GO:0004674 22/94 protein serine/threonine kinase activity molecular_function "Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate." [GOC:bf] EOG8S7N4H GO:0004683 2/94 calmodulin-dependent protein kinase activity molecular_function "Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin." [GOC:mah, PMID:11264466] EOG8S7N4H GO:0004672 2/94 protein kinase activity molecular_function "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP." [MetaCyc:PROTEIN-KINASE-RXN] EOG8S7N4H GO:0005874 1/94 microtubule cellular_component "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568] EOG8S7N4H GO:0005635 1/94 nuclear envelope cellular_component "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." [ISBN:0198547684] EOG8S7N4H GO:0005813 1/94 centrosome cellular_component "A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle." [GOC:mah, ISBN:0198547684] EOG8S7N4H GO:0046580 1/94 negative regulation of Ras protein signal transduction biological_process "Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction." [GOC:bf] EOG8S7N4H GO:0051019 1/94 mitogen-activated protein kinase binding molecular_function "Interacting selectively and non-covalently with a mitogen-activated protein kinase." [GOC:ai] EOG8S7N4H GO:0006468 1/94 protein phosphorylation biological_process "The process of introducing a phosphate group on to a protein." [GOC:hb] EOG8S7N4H GO:0016301 1/94 kinase activity molecular_function "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] EOG8S7N4H GO:0007017 1/94 microtubule-based process biological_process "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." [GOC:mah] EOG8S7N4H GO:0040008 1/94 regulation of growth biological_process "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." [GOC:ems, GOC:mah] EOG8S7N4H GO:0005737 1/94 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684]