EOG8SBHBP GO:0008270 24/96 zinc ion binding molecular_function "Interacting selectively and non-covalently with zinc (Zn) ions." [GOC:ai] EOG8SBHBP GO:0043565 20/96 sequence-specific DNA binding molecular_function "Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding." [GOC:jl] EOG8SBHBP GO:0003700 20/96 transcription factor activity, sequence-specific DNA binding molecular_function "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex." [GOC:curators, GOC:txnOH] EOG8SBHBP GO:0005634 16/96 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8SBHBP GO:0035097 8/96 histone methyltransferase complex cellular_component "A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins." [GOC:bf] EOG8SBHBP GO:0008168 8/96 methyltransferase activity molecular_function "Catalysis of the transfer of a methyl group to an acceptor molecule." [ISBN:0198506732] EOG8SBHBP GO:0042800 8/96 histone methyltransferase activity (H3-K4 specific) molecular_function "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein." [PMID:12086618] EOG8SBHBP GO:0006351 3/96 transcription, DNA-templated biological_process "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH] EOG8SBHBP GO:0018024 2/96 histone-lysine N-methyltransferase activity molecular_function "Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives." [EC:2.1.1.43, RESID:AA0074, RESID:AA0075, RESID:AA0076] EOG8SBHBP GO:0051568 1/96 histone H3-K4 methylation biological_process "The modification of histone H3 by addition of a methyl group to lysine at position 4 of the histone." [GOC:ai] EOG8SBHBP GO:0032968 1/96 positive regulation of transcription elongation from RNA polymerase II promoter biological_process "Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II." [GOC:mah, GOC:txnOH] EOG8SBHBP GO:0044212 1/96 transcription regulatory region DNA binding molecular_function "Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors." [GOC:jl, GOC:txnOH, SO:0005836] EOG8SBHBP GO:0003723 1/96 RNA binding molecular_function "Interacting selectively and non-covalently with an RNA molecule or a portion thereof." [GOC:mah] EOG8SBHBP GO:0042803 1/96 protein homodimerization activity molecular_function "Interacting selectively and non-covalently with an identical protein to form a homodimer." [GOC:jl] EOG8SBHBP GO:0003899 1/96 DNA-directed RNA polymerase activity molecular_function "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'." [EC:2.7.7.6] EOG8SBHBP GO:0042802 1/96 identical protein binding molecular_function "Interacting selectively and non-covalently with an identical protein or proteins." [GOC:jl] EOG8SBHBP GO:0003682 1/96 chromatin binding molecular_function "Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." [GOC:jl, ISBN:0198506732, PMID:20404130] EOG8SBHBP GO:0043966 1/96 histone H3 acetylation biological_process "The modification of histone H3 by the addition of an acetyl group." [GOC:jl] EOG8SBHBP GO:0005515 1/96 protein binding molecular_function "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GOC:go_curators] EOG8SBHBP GO:0005875 1/96 microtubule associated complex cellular_component "Any multimeric complex connected to a microtubule." [GOC:jl] EOG8SBHBP GO:0007275 1/96 multicellular organismal development biological_process "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] EOG8SBHBP GO:0008354 1/96 germ cell migration biological_process "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." [GOC:bf, GOC:jl] EOG8SBHBP GO:0016571 1/96 histone methylation biological_process "The modification of histones by addition of methyl groups." [GOC:ai] EOG8SBHBP GO:0044665 1/96 MLL1/2 complex cellular_component "A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species." [GOC:sart, PMID:21875999] EOG8SBHBP GO:0008023 1/96 transcription elongation factor complex cellular_component "Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation." [GOC:jl] EOG8SBHBP GO:0005700 1/96 polytene chromosome cellular_component "A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible." [ISBN:0198506732] EOG8SBHBP GO:0007411 1/96 axon guidance biological_process "The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues." [ISBN:0878932437] EOG8SBHBP GO:2001020 1/96 regulation of response to DNA damage stimulus biological_process "Any process that modulates the frequency, rate or extent of response to DNA damage stimulus." [GOC:obol] EOG8SBHBP GO:0008157 1/96 protein phosphatase 1 binding molecular_function "Interacting selectively and non-covalently with the enzyme protein phosphatase 1." [GOC:jl]