EOG8WHC1D GO:0070403 19/59 NAD+ binding molecular_function "Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah] EOG8WHC1D GO:0005654 1/59 nucleoplasm cellular_component "That part of the nuclear content other than the chromosomes or the nucleolus." [GOC:ma, ISBN:0124325653] EOG8WHC1D GO:0006355 1/59 regulation of transcription, DNA-templated biological_process "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." [GOC:go_curators, GOC:txnOH] EOG8WHC1D GO:0042981 1/59 regulation of apoptotic process biological_process "Any process that modulates the occurrence or rate of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] EOG8WHC1D GO:0017136 1/59 NAD-dependent histone deacetylase activity molecular_function "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone." [EC:3.5.1.17, RHEA:24551] EOG8WHC1D GO:0004407 1/59 histone deacetylase activity molecular_function "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes." [EC:3.5.1.98, PMID:9893272] EOG8WHC1D GO:0008340 1/59 determination of adult lifespan biological_process "The control of viability and duration in the adult phase of the life-cycle." [GOC:ems] EOG8WHC1D GO:0008134 1/59 transcription factor binding molecular_function "Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription." [ISBN:0198506732] EOG8WHC1D GO:0005634 1/59 nucleus cellular_component "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] EOG8WHC1D GO:0016575 1/59 histone deacetylation biological_process "The modification of histones by removal of acetyl groups." [GOC:ai] EOG8WHC1D GO:0006342 1/59 chromatin silencing biological_process "Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin." [GOC:mah, PMID:10219245] EOG8WHC1D GO:2000253 1/59 positive regulation of feeding behavior biological_process "Any process that activates or increases the frequency, rate or extent of feeding behavior." [GOC:obol] EOG8WHC1D GO:0046872 1/59 metal ion binding molecular_function "Interacting selectively and non-covalently with any metal ion." [GOC:ai] EOG8WHC1D GO:0048149 1/59 behavioral response to ethanol biological_process "Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus." [GOC:jid] EOG8WHC1D GO:0005737 1/59 cytoplasm cellular_component "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] EOG8WHC1D GO:0035065 1/59 regulation of histone acetylation biological_process "Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein." [GOC:bf] EOG8WHC1D GO:0006351 1/59 transcription, DNA-templated biological_process "The cellular synthesis of RNA on a template of DNA." [GOC:jl, GOC:txnOH]