Domain arrangement Fusions Fissions Terminal losses Terminal emergences Single domain losses Single domain emergences PF00010 0 1 0 0 0 0 PF00069 PF00566 PF00581 1 0 0 0 0 0 PF00069 PF12474 1 0 0 0 0 0 PF00077 PF00078 1 0 0 0 0 0 PF00089 0 1 0 0 0 0 PF00169 PF08718 1 0 0 0 0 0 PF00173 PF00970 PF00175 1 0 0 0 0 0 PF00240 PF03031 1 0 0 0 0 0 PF00249 PF04433 1 0 0 0 0 0 PF00270 PF00271 PF16124 PF09382 0 0 1 0 0 0 PF00568 PF00786 1 0 0 0 0 0 PF00579 PF01588 1 0 0 0 0 0 PF00595 PF00625 1 0 0 0 0 0 PF00611 PF10291 1 0 0 0 0 0 PF00621 PF00618 PF00617 1 0 0 0 0 0 PF00628 PF13621 1 0 0 0 0 0 PF00641 PF02338 1 0 0 0 0 0 PF00642 PF00097 1 0 0 0 0 0 PF00643 PF00439 1 0 0 0 0 0 PF00754 PF07714 1 0 0 0 0 0 PF00787 PF00069 PF00433 1 0 0 0 0 0 PF00868 0 1 2 0 0 0 PF00989 PF14598 0 1 0 0 0 0 PF01145 PF02036 1 0 0 0 0 0 PF01344 PF13415 1 0 0 0 0 0 PF01411 PF07973 1 0 0 0 0 0 PF01437 PF01833 PF08337 1 0 0 0 0 0 PF01472 PF01189 1 0 0 0 0 0 PF01841 0 1 0 0 0 0 PF01990 0 0 0 0 1 0 PF02033 0 0 0 0 1 0 PF02138 PF00400 1 0 0 0 0 0 PF02145 PF00780 1 0 0 0 0 0 PF02259 PF00454 1 0 0 0 0 0 PF02375 PF02373 PF13831 PF13832 1 0 0 0 0 0 PF02759 PF13901 1 0 0 0 0 0 PF02791 0 0 2 0 0 0 PF02819 0 0 0 0 1 0 PF02854 PF02847 1 0 0 0 0 0 PF02881 PF00448 0 0 2 0 0 0 PF03097 PF13949 PF00102 1 0 0 0 0 0 PF03732 PF00098 1 0 0 0 0 0 PF05672 0 0 0 0 1 0 PF05953 0 0 0 0 1 0 PF06699 0 0 0 0 1 0 PF06730 0 0 0 0 1 0 PF06747 0 0 0 0 1 0 PF07679 PF00089 1 0 0 0 0 0 PF07679 PF13927 PF00041 PF00102 1 0 0 0 0 0 PF07686 PF08205 PF13927 PF13895 1 0 0 0 0 0 PF07809 0 0 0 0 1 0 PF07896 0 0 0 0 1 0 PF08265 0 0 1 0 0 0 PF08513 0 1 0 0 0 0 PF09038 0 0 0 0 1 0 PF09379 PF00373 PF09380 PF00102 1 0 0 0 0 0 PF09469 0 0 0 0 1 0 PF09741 0 0 0 0 1 0 PF09750 PF01805 1 0 0 0 0 0 PF09770 0 0 0 0 1 0 PF10190 0 0 0 0 1 0 PF10215 0 0 0 0 1 0 PF10441 0 0 0 0 1 0 PF10491 0 0 1 0 0 0 PF10495 0 0 0 0 1 0 PF10513 PF13831 PF13832 1 0 0 0 0 0 PF10607 0 1 0 0 0 0 PF11365 0 0 0 0 1 0 PF11969 0 0 1 0 0 0 PF12032 0 1 0 0 0 0 PF12190 0 0 0 0 1 0 PF12333 0 0 0 0 1 0 PF12698 PF00005 PF12698 1 0 0 0 0 0 PF12796 PF00651 1 0 0 0 0 0 PF12796 PF07714 1 0 0 0 0 0 PF12796 PF11904 1 0 0 0 0 0 PF12796 PF13606 PF07525 1 0 0 0 0 0 PF12796 PF13637 PF00023 1 0 0 0 0 0 PF12836 PF12937 PF00400 1 0 0 0 0 0 PF12872 PF00567 1 0 0 0 0 0 PF12874 PF13912 PF12874 1 0 0 0 0 0 PF12937 PF00179 1 0 0 0 0 0 PF12937 PF00622 1 0 0 0 0 0 PF13281 PF00069 1 0 0 0 0 0 PF13639 PF00628 1 0 0 0 0 0 PF13855 PF00307 1 0 0 0 0 0 PF13905 PF01436 1 0 0 0 0 0 PF14555 PF00789 1 0 0 0 0 0 PF14645 0 0 0 0 1 0 PF14735 0 0 0 0 1 0 PF14929 0 0 0 0 1 0 PF15065 0 0 0 0 1 0 PF15071 0 0 0 0 1 0