Domain arrangement Fusions Fissions Terminal losses Terminal emergences Single domain losses Single domain emergences PF00035 PF16482 PF05018 1 0 0 0 0 0 PF00043 0 1 0 0 0 0 PF00047 PF07679 PF13927 PF07679 PF00041 1 0 0 0 0 0 PF00054 PF00008 PF00054 0 1 0 0 0 0 PF00060 PF14727 PF14728 1 0 0 0 0 0 PF00063 PF06017 0 1 0 0 0 0 PF00069 PF00629 1 0 0 0 0 0 PF00076 0 1 0 0 0 0 PF00095 PF00041 1 0 0 0 0 0 PF00096 PF13912 PF00083 1 0 0 0 0 0 PF00097 PF00643 PF01436 1 0 0 0 0 0 PF00105 PF00104 PF00400 PF04192 1 0 0 0 0 0 PF00132 PF02020 1 0 0 0 0 0 PF00159 0 0 0 0 1 0 PF00160 PF16040 PF16041 1 0 0 0 0 0 PF00225 PF00787 1 0 0 0 0 0 PF00240 PF12148 PF00628 PF02182 PF00097 1 0 0 0 0 0 PF00244 PF00365 1 0 0 0 0 0 PF00248 0 1 0 0 0 0 PF00397 PF00168 1 0 0 0 0 0 PF00400 0 1 0 0 0 0 PF00415 PF00651 PF07707 1 0 0 0 0 0 PF00493 0 0 6 0 0 0 PF00515 PF13181 0 0 3 0 0 0 PF00530 PF13229 1 0 0 0 0 0 PF00561 PF00962 1 0 0 0 0 0 PF00564 0 1 2 0 0 0 PF00564 PF00569 0 0 1 0 0 0 PF00595 0 1 0 0 0 0 PF00595 PF00787 PF00788 1 0 0 0 0 0 PF00595 PF01369 PF15410 1 0 0 0 0 0 PF00620 PF00788 1 0 0 0 0 0 PF00621 PF00620 1 0 1 0 0 0 PF00732 PF05199 PF00732 PF05199 1 0 0 0 0 0 PF00831 0 0 0 0 1 0 PF00855 PF03446 PF14833 1 0 0 0 0 0 PF00994 0 0 4 0 0 0 PF01431 0 1 0 0 0 0 PF01433 0 1 0 0 0 0 PF01435 0 0 1 0 0 0 PF01448 PF03154 1 0 0 0 0 0 PF01471 PF00413 0 0 1 0 0 0 PF01490 PF00292 PF00046 1 0 0 0 0 0 PF01562 PF13688 PF00200 0 0 1 0 0 0 PF01777 0 0 1 0 0 0 PF02137 0 1 0 0 0 0 PF02185 PF03097 PF00595 0 1 0 0 0 0 PF02210 0 1 0 0 0 0 PF02214 PF00805 0 0 1 0 0 0 PF02318 PF00168 1 0 0 0 0 0 PF02318 PF00595 PF00168 1 0 0 0 0 0 PF02535 PF03066 1 0 0 0 0 0 PF03015 PF07686 1 0 0 0 0 0 PF03083 PF00076 1 0 0 0 0 0 PF03133 PF07776 PF13894 1 0 0 0 0 0 PF03645 PF00328 1 0 0 0 0 0 PF03810 PF08506 0 0 1 0 0 0 PF04053 PF06957 0 1 0 0 0 0 PF04161 0 0 0 0 1 0 PF04434 0 0 0 0 1 0 PF04568 0 1 0 0 0 0 PF04675 PF01068 0 0 1 0 0 0 PF05375 0 0 0 0 1 0 PF05605 0 0 1 0 0 0 PF05649 0 1 0 0 0 0 PF05699 0 0 1 0 0 0 PF05773 PF01485 1 0 0 0 0 0 PF05958 0 1 0 0 0 0 PF06371 PF06367 PF02181 PF06345 0 1 0 0 0 0 PF06468 PF00090 1 0 0 0 0 0 PF06522 0 0 0 0 1 0 PF07156 0 0 1 0 0 0 PF07686 PF08205 PF13927 PF00041 1 0 0 0 0 0 PF07776 PF13894 PF12874 1 0 0 0 0 0 PF07776 PF13894 PF12874 PF13912 1 0 0 0 0 0 PF08257 0 0 0 0 1 0 PF08585 PF06003 1 0 0 0 0 0 PF09302 0 0 0 0 1 0 PF09380 PF08736 0 0 2 0 0 0 PF10602 PF01399 PF00929 1 0 0 0 0 0 PF10613 PF00060 PF10613 PF00060 1 0 0 0 0 0 PF11838 0 1 0 0 0 0 PF11904 0 1 0 0 0 0 PF12796 0 1 0 0 0 0 PF12796 PF00023 PF12796 PF07693 1 0 0 0 0 0 PF12796 PF00023 PF12796 PF13637 PF12796 1 0 0 0 0 0 PF12796 PF00536 1 0 0 0 0 0 PF12796 PF13606 0 0 7 0 0 0 PF12874 PF13894 1 0 0 0 0 0 PF12874 PF13894 PF13912 PF13894 1 0 0 0 0 0 PF12894 PF12816 1 0 0 0 0 0 PF12937 0 2 0 0 0 0 PF13306 PF13855 PF01582 1 0 0 0 0 0 PF13369 PF08755 0 1 0 0 0 0 PF13405 0 0 4 0 0 0 PF13417 0 1 2 0 0 0 PF13426 PF00233 PF00011 1 0 0 0 0 0 PF13499 PF10506 1 0 0 0 0 0 PF13637 PF00788 1 0 0 0 0 0 PF13855 PF00560 PF13855 PF13306 1 0 0 0 0 0 PF13873 0 1 0 0 0 0 PF13927 PF07679 PF07714 1 0 0 0 0 0 PF13961 0 1 0 0 0 0 PF14050 PF16273 PF04969 1 0 0 0 0 0 PF14223 0 1 0 0 0 0 PF14604 0 1 0 0 0 0 PF14604 PF08824 PF12026 1 0 0 0 0 0 PF14844 PF02138 PF00400 1 0 0 0 0 0 PF15469 0 0 1 0 0 0 PF15886 0 0 1 0 0 0 PF16563 0 1 0 0 0 0