GO:0004364	glutathione transferase activity	Gains
GO:0004602	glutathione peroxidase activity	Gains
GO:0004104	cholinesterase activity	Gains
GO:0003990	acetylcholinesterase activity	Gains
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	Gains
GO:0004190	aspartic-type endopeptidase activity	Gains
GO:0070001	aspartic-type peptidase activity	Gains
GO:0016860	intramolecular oxidoreductase activity	Gains
GO:0033780	taurochenodeoxycholate 6alpha-hydroxylase activity	Gains
GO:0018833	DDT-dehydrochlorinase activity	Gains
GO:0005550	pheromone binding	Gains
GO:0004667	prostaglandin-D synthase activity	Gains
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	Gains
GO:0004601	peroxidase activity	Gains
GO:0033777	lithocholate 6beta-hydroxylase activity	Gains
GO:0031386	protein tag	Gains
GO:0004348	glucosylceramidase activity	Gains
GO:0046423	allene-oxide cyclase activity	Gains
GO:0047396	glycosylphosphatidylinositol diacylglycerol-lyase activity	Gains
GO:0016848	carbon-halide lyase activity	Gains
GO:0050220	prostaglandin-E synthase activity	Gains
GO:0050591	quinine 3-monooxygenase activity	Gains
GO:0016209	antioxidant activity	Gains
GO:0005549	odorant binding	Gains
GO:0016802	trialkylsulfonium hydrolase activity	Gains
GO:0004013	adenosylhomocysteinase activity	Gains
GO:0008233	peptidase activity	Gains
GO:0003950	NAD+ ADP-ribosyltransferase activity	Gains
GO:0016829	lyase activity	Gains
GO:0003796	lysozyme activity	Gains
GO:0004344	glucose dehydrogenase activity	Gains
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Gains
GO:0070330	aromatase activity	Gains
GO:0003677	DNA binding	Gains
GO:0003747	translation release factor activity	Gains
GO:0016801	hydrolase activity, acting on ether bonds	Gains
GO:0008079	translation termination factor activity	Gains
GO:0003676	nucleic acid binding	Gains
GO:0016853	isomerase activity	Gains
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	Gains
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	Gains
GO:0008812	choline dehydrogenase activity	Gains
GO:0004089	carbonate dehydratase activity	Gains
GO:0003964	RNA-directed DNA polymerase activity	Losses
GO:0016779	nucleotidyltransferase activity	Losses
GO:0034061	DNA polymerase activity	Losses
GO:0004334	fumarylacetoacetase activity	Losses
GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds	Losses
GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances	Losses
GO:0050897	cobalt ion binding	Losses
GO:0004038	allantoinase activity	Losses
GO:0035198	miRNA binding	Losses
GO:0140097	catalytic activity, acting on DNA	Losses
GO:0034736	cholesterol O-acyltransferase activity	Losses
GO:0004772	sterol O-acyltransferase activity	Losses
GO:0004519	endonuclease activity	Losses
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	Losses
GO:0016859	cis-trans isomerase activity	Losses
GO:0035197	siRNA binding	Losses
GO:0047915	ganglioside galactosyltransferase activity	Losses
GO:0008036	diuretic hormone receptor activity	Losses
GO:0005154	epidermal growth factor receptor binding	Losses
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	Losses
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	Losses
GO:0003960	NADPH:quinone reductase activity	Losses
GO:0004687	myosin light chain kinase activity	Losses
GO:0034062	5'-3' RNA polymerase activity	Losses
GO:0097747	RNA polymerase activity	Losses
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	Losses
GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity	Losses
GO:0070851	growth factor receptor binding	Losses
GO:0008194	UDP-glycosyltransferase activity	Losses
GO:0004334	fumarylacetoacetase activity	Extinctions
GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds	Extinctions
GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances	Extinctions
GO:0050897	cobalt ion binding	Extinctions
GO:0004038	allantoinase activity	Extinctions
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	Extinctions
GO:0016859	cis-trans isomerase activity	Extinctions
GO:0034736	cholesterol O-acyltransferase activity	Extinctions
GO:0004772	sterol O-acyltransferase activity	Extinctions
GO:0047915	ganglioside galactosyltransferase activity	Extinctions
GO:0008036	diuretic hormone receptor activity	Extinctions
GO:0005154	epidermal growth factor receptor binding	Extinctions
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	Extinctions
GO:0008194	UDP-glycosyltransferase activity	Extinctions
GO:0003960	NADPH:quinone reductase activity	Extinctions
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	Extinctions
GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity	Extinctions
GO:0070851	growth factor receptor binding	Extinctions
GO:0035250	UDP-galactosyltransferase activity	Extinctions
GO:0003964	RNA-directed DNA polymerase activity	Extinctions